Advanced special topics course in metabolomics 2025
(GBSC 724)
Course will be held on Mondays, Wednesdays and Fridays 9-10:30 am in the SHELBY 1115
Tentative Schedule
The PowerPoint versions are available on request to sbarnes@uab.edu.
| Date | Lecturer | Topic |
|---|---|---|
| Jan 8, Wed | S. Barnes | Transition from metabolism to metabolomics and targeted/untargeted approaches |
| Jan 10, Fri | S. Barnes | A review of central metabolism in living tissues |
| Jan 13, Mon | H. Tiwari | Designing a complex metabolomics experiment |
| Jan 15, Wed | W. Placzek | The platform - fundamentals in NMR and metabolomics |
| Jan 17, Fri | S. Barnes | The platform – fundamentals in GC- and LC-mass spectrometry |
| Jan 20, MOn | No Class | Martin Luther King Holiday |
| Jan 22, Wed | J. Prasain | Extracting the metabolome (fluids, cells and tissues) |
| Jan 24, Fri | D. Sharer | Targeted metabolomics for congenital disease in children |
| Jan 27, Mon | J. Prasain | MSMS of small molecules - interpretation |
| Jan 29, Wed | J. Prasain | SWATH-MS, Ion Mobility and LC-MS for lipidomics |
| Jan 31, Fri | W. Placzek | Processing NMR data |
| Feb 3, Mon | No Class | At Gordon Conference |
| Feb 5, Wed | No Class | At Gordon Conference |
| Feb 7, Fri | No Class | At Gordon Conference |
| Feb 10, Mon | Students’ presentations | |
| Feb 12, Wed | S. Barnes | MS-DIAL– a comprehensive metabolomics tool – bring PC to this class |
| Feb 14, Fri | M. Wang* | GNPS analysis of MS-DIAL data |
| Feb 17, Mon | S. Barnes | Statistical analysis of MS-DIAL data with MetaboAnalyst 6.0 |
| Feb 19 Wed | S. Barnes | MZmine 2.53, 3 and 4.1 hands-on class exercise |
| Feb 21, Fri | S. Barnes | Pathway databases and Metabolomics Workbench |
| Feb 24, Mon | J. Mitchell** | Asari – accelerating metabolomics data analysis |
| Feb 26, Wed | The TMAO story and follow up – Students’ presentations | |
| Feb 28, Fri | S. Barnes | Bile acid metabolism |
| Mar 3, Mon | Robert Quinn*** | Novel bile acid-microbiome interactions |
| Mar 5, Mon | S. Barnes | Peaks-to-pathways - Mummichog analysis of data |
| Mar 7, Wed | C. Beecher**** | Isotope Ratio Outlier Analysis (IROA) - video |
| Mar 10, Fri | C. Beecher**** | Building a metabolite standards database |
| Mar 12, Wed | S. Barnes | Isotopes and pathway dynamics |
| Mar 14, Fri | Student presentations | |
| Mar 17, Mon | Mario Uchimiya***** | NMR metabolomics |
| Mar 19, Wed | J. Prasain | Lipid maps database |
| Mar 21, Fri | J. Prasain | Validating metabolites and novel prostanoid molecules |
| Mar 24, Mon | Student presentations | |
| Mar 26, Wed | S. Barnes | In situ lipidomics in the surgical suite |
| Mar 28, Fri | Juhi Samal | DESI imaging-mass spectrometry |
| Mar 31, Mon | S. Barnes | Metabolomics in clinical studies |
| Apr 2, Wed | Laura Reed (UA) | Integrating the metabolome with the genome and transcriptome in the context of environmental exposure in the fruit fly (video) |
| Apr 4, Fri | S. Barnes | TBA |
| Apr 7, Mon | T. Marquez-Lago | Machine learning and artificial intelligence and its application to metabolomics |
| Apr 9, Wed | Jianhua Zhang | Measurement of mitochondrial function using the Seahorse extracellular flux bioanalyzer |
| Apr 11, Fri | S. Barnes | Metabolomics and microbiome |
| Apr 14, Mon | X. Hu****** | Integration of -omics data |
| Apr 21, Mon | FINAL exam due |
*UC-Irvine
**Jackson Labs
***Michigan State U.
****IROA Technologies
*****U. Georgia
******Emory U.