Authors:
Kristina Tymes-Wilbekin1, 2, 3
Patrice L. Capers1
Austin Clark4, 5
Kathryn A. Kaiser1
Departments:
1. Office of Energetics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
2. PARAdiGM Program, University of Alabama at Birmingham, Birmingham, AL, USA
3. Spelman College, Atlanta, GA, USA
4. Summer in Biomedical Sciences (SIBS) Undergraduate Research Program, University of Alabama at Birmingham, Birmingham, AL, USA
5. University of West Florida, Pensacola, FL, USA
Abstract
Background: The Centers for Disease Control and Prevention has acknowledged the growing epidemic of childhood obesity and, with it, the likelihood of an increasing percentage of obese adults in the coming years. This problem raises alarm because more people will be susceptible to heart disease, type 2 diabetes and other weight-related illnesses. Thus far, effective interventions have proven elusive.
Methods: We conducted a meta-analysis of pediatric obesity behavioral interventions to examine the effect for improving weight/body composition. We reviewed 14 studies (total N = 3,363) that examined the effects of behavioral therapies on weight change (reduced weight gain while growing or reduced body fat percentage) in children. The studies included are randomized control trials (RCTs) from a prior systematic review that documented weight change as a primary or secondary outcome and were published between January 2007 and July 2009. Using standard meta-analytic methods, we quantified effects to determine whether behavioral therapies are effective in improving body weight/body composition in children.
Results: The overall standardized mean difference of -0.23 with a 95% Confidence Interval of -0.38 to -0.07 indicates that behavioral therapies do have a significant effect as an intervention for improving weight outcomes in children. There was significant heterogeneity present (I2 = 61%, p = 0.0003).
Conclusions: Behavioral interventions may be superior to other types of obesity interventions in children. Larger studies are warranted. These results may be utilized to treat patients, create policies and better inform the public. Future studies might increase intervention duration, which might improve maintenance of effects post-intervention. Keywords: pediatric obesity, behavioral intervention, weight maintenance, meta-analysis.
References
- Childhood Obesity Facts. Centers for Disease Control and Prevention. 2014. Available from: http://www.cdc.gov/healthyyouth/obesity/facts.htm.
- Daniels, S.R., Arnett, D.K., Eckel, R.H., Gidding, S.S., Hayman, L.L., Kumanyika, S., et al. Overweight in children and adolescents: pathophysiology, consequences, prevention, and treatment. Circulation. 111(15), 1999–2012 (2005).
- Ebbeling, C.B., Pawlak, D.B. & Ludwig, D.S. Childhood obesity: public-health crisis, common sense cure. Lancet. 360(9331), 473–82 (2002).
- Freedman, D.S., Khan, L.K., Serdula, M.K., Dietz, W.H., Srinivasan, S.R. & Berenson, G.S. The relation of childhood BMI to adult adiposity: the Bogalusa Heart Study. Pediatrics. 115(1), 22–7 (2005).
- Affuso, O., Kaiser, K.A., Carson, T.L., Ingram, K.H., Schwiers, M., Robertson, H., et al. Association of run-in periods with weight loss in obesity randomized controlled trials. M Obesity reviews. 15(1), 68–73 (2014).
- Wilfley, D.E., Kolko, R.P. & Kass, A.E. Cognitive-behavioral therapy for weight management and eating disorders in children and adolescents. Child and adolescent psychiatric clinics of North America. 20(2), 271–85 (2011).
- Doyle, A.C., Goldschmidt, A., Huang, C., Winzelberg, A.J., Taylor, C.B. & Wilfley, D.E. Reduction of overweight and eating disorder symptoms via the Internet in adolescents: a randomized controlled trial. The Journal of adolescent health. 43(2), 172–9 (2008).
- Epstein, L.H., Roemmich, J.N., Robinson, J.L., Paluch, R.A., Winiewicz, D.D., Fuerch, J.H., et al. A randomized trial of the effects of reducing television viewing and computer use on body mass index in young children. Archives of pediatrics & adolescent medicine. 162(3), 239–45 (2008).
- Foster, G.D., Sherman, S., Borradaile, K.E., Grundy, K.M., Vander Veur, S.S., Nachmani, J., et al. A policy-based school intervention to prevent overweight and obesity. Pediatrics. 121(4), e794–802 (2008).
- Golley, R.K., Magarey, A.M., Baur, L.A., Steinbeck, K.S. & Daniels, L.A. Twelve-month effectiveness of a parent-led, family-focused weight-management program for prepubertal children: a randomized, controlled trial. Pediatrics. 119(3), 517–25 (2007).
- Janicke, D.M., Sallinen, B.J., Perri, M.G., Lutes, L.D., Huerta, M., Silverstein, J.H., et al. Comparison of parent-only vs family-based interventions for overweight children in underserved rural settings: outcomes from project STORY. Archives of pediatrics & adolescent medicine. 162(12), 1119–25 (2008).
- Kalavainen, M.P., Korppi, M.O. & Nuutinen, O.M. Clinical efficacy of group-based treatment for childhood obesity compared with routinely given individual counseling. International journal of obesity. 31(10), 1500–8 (2007).
- Kitzman-Ulrich, H., Hampson, R., Wilson, D.K., Presnell, K., Brown, A. & O'Boyle, M. An adolescent weight-loss program integrating family variables reduces energy intake. Journal of the American Dietetic Association. 109(3), 491–6 (2009).
- McCallum, Z., Wake, M., Gerner, B., Baur, L.A., Gibbons, K., Gold, L., et al. Outcome data from the LEAP (Live, Eat and Play) trial: a randomized controlled trial of a primary care intervention for childhood overweight/mild obesity. International journal of obesity. 31(4), 630–6 (2007).
- Shelton, D., Le Gros, K., Norton, L., Stanton-Cook, S., Morgan, J. & Masterman, P. Randomised controlled trial: A parent-based group education programme for overweight children. Journal of paediatrics and child health. 43(12), 799–805 (2007).
- Sichieri, R., Paula Trotte, A., de Souza, R.A., Veiga, G.V. School randomised trial on prevention of excessive weight gain by discouraging students from drinking sodas. Public health nutrition. 12(2), 197–202 (2009).
- Tsiros, M.D., Sinn, N., Brennan, L., Coates, A.M., Walkley, J.W., Petkov, J., et al. Cognitive behavioral therapy improves diet and body composition in overweight and obese adolescents. The American journal of clinical nutrition. 87(5), 1134–40 (2008).
- Walsh, S.M., Palmer, W., Welsh, J.A. & Vos, M.B. Challenges and successes of a multidisciplinary pediatric obesity treatment program. Nutrition in clinical practice. 29(8), 780–785 (2014).
- Wilfley, D.E., Stein, R.I., Saelens, B.E., Mockus, D.S., Matt, G.E., Hayden-Wade, H.A., et al. Efficacy of maintenance treatment approaches for childhood overweight: a randomized controlled trial. JAMA. 298(14), 1661–73 (2007).
- Cochrane Handbook for Systematic Reviews of Interventions: The Cochrane Collaboration. 2009. Available from: www.cochrane-handbook.org.
- Collaboration. The Cochrane Collaboration. Review Manager Version 5.3. Copenhagen: The Nordic Cochrane Centre. 2012.