UAB Comprehensive Diabetes Center (UCDC) Associate Director Ambika Ashraf, M.D., published the review “Altered lipid metabolism and the development of metabolic-associated fatty liver disease” in the journal Current Opinion in Lipidology.

Ashraf is also the Ralph Froshin Endowed Chair in Pediatric Endocrinology, the director of the Pediatric Lipid Clinic, and the associate director of Metabolic Bone Clinic.

Authors note that their publication is a review that examines the intricate relationship between lipoprotein abnormalities and the development of metabolic-associated fatty liver disease (MAFLD).

MAFLD, previously known as non-alcoholic fatty liver disease, is often used to describe fatty liver disease in patients with a genetic predisposition compounded by metabolic conditions such as insulin resistance and systemic metabolic stress.

Within the review, authors cover predispositions of MAFLD, therapeutic strategies for lifestyle interventions, lipid lowering medications, and more.

Ashraf collaborated with First Author Christy Foster, M.D., assistant professor in the UAB Department of Pediatrics, Division of Pediatric Endocrinology, as well as Charles Gagnon, medical student in the UAB Heersink School of Medicine.