Padgett LE and Tse HM. 2016. NADPH Oxidase-Derived Superoxide Provides a Third Signal for CD4 T cell Effector Responses. Journal of Immunology 197(5):1733-42 PMC4992601
Tse HM, Kozlovskaya V, Kharlampieva, and Hunter CS. 2015. Mini-review: Directed differentiation and encapsulation of islet beta-cells: recent advances and future considerations. Molecular Endocrinology 29(10):805-812. PMC4588727
Padgett LE, Anderson B, Liu C, Ganini D, Mason RP, Piganelli JD, Mathews CE, and Tse HM. 2015. Loss of NOX-Derived Superoxide Exacerbates Diabetogenic CD4 T cell Effector Responses in Type 1 Diabetes. Diabetes 64(12):4171-4183. PMC4657579
Kozlovskaya V, Xue B, Lei W, Padgett LE, Tse HM*, and Kharlampieva E. 2015. Hydrogen-Bonded Multilayers of Tannic Acid as Mediators of T cell Immunity. Advanced Healthcare Materials 4(5):686-694. PMC4390483. * co-corresponding author.
Padgett LE, Burg AB, Lei W, and Tse HM 2015. Loss of NADPH Oxidase-Derived Superoxide Skews Macrophage Phenotypes to Delay Type 1 Diabetes. Diabetes 64(3):937-946. PMCID: PMC4338593
Padgett LE, Burg AR, Lei W, Tse HM. 2014. Loss of NADPH Oxidase-Derived Superoxide Skews Macrophage Phenotypes to Delay Type 1 Diabetes. Diabetes. [Epub ahead of print] PMID:25288672
Bone RN, Gai Y, Magrioti V, Kokotou MG, Ali T, Lei X, Tse HM, Kokotos G, Ramanadham S. 2014. Inhibition of Ca2+-Independent Phospholipase A2 (iPLA2β) Ameliorates Islet Infiltration and Incidence of Diabetes in NOD Mice. Diabetes. [Epub ahead of print] PMID:25213337
Lei X, Bone RN, Ali T, Zhang S, Bohrer A, Tse HM, Bidasee KR, Ramanadham S. 2014. Evidence of contribution of iPLA2β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2β in T1D development. Endocrinology. 155(9):3352-64. PMID:25004092 PMCID:PMC4138580
Sawant A, Schafer CC, Jin TH, Zmijewski J, Tse HM, Roth J, Sun Z, Siegal GP, Thannickal VJ, Grant SC, Ponnazhagan S, Deshane JS. 2013. Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways. Cancer Res. 73(22):6609-20. PMID:24085788 PMCID:PMC3854493
Casazza K, Hanks LJ, Clines GA, Tse HM, Eberhardt AW. 2013. Diabetes-related impairment in bone strength is established early in the life course. World J Diabetes. 4(4):145-50. PMID:23961325 PMCID:PMC3746087
Kozlovskaya V, Zavgorodnya O, Chen Y, Ellis K, Tse HM, Cui W, Thompson JA, Kharlampieva E. 2012. Ultrathin polymeric coatings based on hydrogen-bonded polyphenol for protection of pancreatic islet cells. Adv Funct Mater. 22(16):3389-3398. PMID:23538331 PMCID:PMC3607452
Delmastro-Greenwood MM, Tse HM, Piganelli JD. 2014. Effects of metalloporphyrins on reducing inflammation and autoimmunity. Antioxid Redox Signal. PMID:23472672
Padgett LE, Broniowska KA, Hansen PA, Corbett JA, Tse HM. 2013. The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis. Ann N Y Acad Sci. 1281:16-35. PMID:23323860 PMCID:PMC3715103
Seleme MC, Lei W, Burg AR, Goh KY, Metz A, Steele C, Tse HM. 2012. Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice. Free Radic Biol Med. 52(9):2047-56. PMID:22361747 PMCID:PMC3711256
Lin MS, Tse HM, Delmastro MM, Bertera S, Wong CT, Lakomy R, He J, Sklavos MM, Coudriet GM, Pietropaolo M, Trucco MM, Piganelli JD. 2011. A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice. Immunol Res. 50(2-3):213-20. PMID:21717080
Thayer TC, Delano M, Liu C, Chen J, Padgett LE, Tse HM, Annamali M, Piganelli JD, Moldawer LL, Mathews CE. 2011. Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes. Diabetes. 60(8):2144-51. PMID:21715554 PMCID:PMC3142064
Sheng H, Spasojevic I, Tse HM, Jung JY, Hong J, Zhang Z, Piganelli JD, Batinic-Haberle I, Warner DS. 2011. Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. J Pharmacol Exp Ther. 338(3):906-16. PMID:21652782 PMCID:PMC3164343
Hager EJ, Piganelli JD, Tse HM, Gibson KM. 2012. Aberrant expression of costimulatory molecules in splenocytes of the mevalonate kinase-deficient mouse model of human hyper-IgD syndrome (HIDS). J Inherit Metab Dis. 35(1):159-68. PMID:21607759 PMCID:PMC3654530
Tse HM, Thayer TC, Steele C, Cuda CM, Morel L, Piganelli JD, Mathews CE. 2010. NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity. J Immunol. 185(9):5247-58. PMID:20881184 PMCID:PMC3190397
Batinic-Haberle I, Spasojevic I, Tse HM, Tovmasyan A, Rajic Z, St Clair DK, Vujaskovic Z, Dewhirst MW, Piganelli JD. 2012. Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities. Amino Acids. 42(1):95-113. Erratum in: Amino Acids. 42(1):115-6. PMID:20473774 PMCID:PMC3022969
Tse HM, Thayer TC, Steele C, Cuda CM, Morel L, Piganelli JD, Mathews CE. 2010. NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity. J Immunol. 185(9):5247-58. PMID: 20881184
Batinic-Haberle I, Spasojevic I, Tse HM, Tovmasyan A, Rajic Z, St Clair DK, Vujaskovic Z, Dewhirst MW, Piganelli JD. 2010. Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities. Amino Acids. 42(1):95-113. PMID: 20473774
Sklavos MM, Bertera S, Tse HM, Bottino R, He J, Beilke JN, Coulombe MG, Gill RG, Crapo JD, Trucco M, Piganelli JD. 2010. Redox modulation protects islets from transplant-related injury. Diabetes. 59(7):1731-8. PMID: 20413509
Su D, Coudriet GM, Kim DH, Lu Y, Perdomo G, Qu S, Slusher S, Tse HM, Piganelli J, Giannoukakis N, Zhang J and Dong HH. 2009. FoxO1 Links Insulin Resistance to Pro-inflammatory Cytokine IL-1beta Production in Macrophages. Diabetes, 58: 2624-2633. PMID: 19651810
Sheng H, Yang W, Fukuda S, Tse HM, Paschen W, Batinic-Haberle I, Crapo JD, Pearlstein RD, Piganelli JD, and Warner DS. 2009. Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat. Free Radical Biology and Medicine, 47: 917-923. PMID: 19631268
Milton-Sklavos MJ, Tse HM, and Piganelli JD. 2008. Redox Modulation Inhibits CD8 T cell Effector Function. Free Radical Biology and Medicine 45:1477-1486. PMID: 18805480
Luppi P, Cifarelli V, Tse HM, Piganelli JD, and Trucco M. 2008. Human C-peptide antagonizes high glucose-induced endothelial dysfunction through the NF-kB pathway. Diabetologia 51:1534-1543. PMID: 18493738
Cifarelli V, Luppi P, Tse HM, He J, Piganelli JD, and Trucco M. 2008. Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-kB activation in vascular smooth muscle cells. Atherosclerosis 201:248-257. PMID: 18294642
Hager EJ, Tse HM, Piganelli JD, Gupt M, Baetscher M, Tse TE, Pappu AS, Steiner RD, Hoffmann GF, and Gibson KM. 2007. Deletion of a Single Mevalonate Kinase (Mvk) Allele Yields a Murine Model of Hyper-IgD Syndrome. Journal of Inherited Metabolic Disease 30:888-895. PMID: 18008182
Tse HM, Milton MJ, Schreiner S, Profozich JL, Trucco M, and Piganelli JD. 2007. Disruption Of Innate-Mediated Pro-Inflammatory Cytokine And Reactive Oxygen Species Third Signal Leads To Antigen-Specific Hyporesponsiveness. Journal of Immunology 178:908-917. PMID: 17202352
Ge X, Piganelli JD, Tse HM, Bertera S, Mathews CE, Trucco M, Wen L, and Rudert WA. 2006. Modulatory Role of DR4- to DQ8-restricted CD4 T-Cell Responses and Type 1 Diabetes Susceptibility. Diabetes 55:3455-3462. PMID: 17130492
Luppi P, Tse H, Lain KY, Markovic N, Piganelli JD, and DeLoia JA. 2006. Preeclampsia activates circulating immune cells with engagement of the NF-kappaB pathway. Am J Reprod Immunol 56 (2):135-144. PMID: 16836616
Bottino R, Balamurugan AN, Tse H, Thirunavukkarasu C, Ge X, Profozich J, Milton M, Ziegenfuss A, Trucco M, and Piganelli JD. 2004. Response of Human Islets to Isolation Stress and the Effect of Antioxidant Treatment. Diabetes 53:2559. PMID: 15448084
Tse HM, Milton MJ, Piganelli JD. 2004. Mechanistic Analysis of the Immunomodulatory Effects of a Catalytic Antioxidant on Antigen Presenting Cells: Implication for Their Use in Targeting Oxidation-Reduction Reactions in Innate Immunity. Free Radic Biol Med 36:233. PMID: 14744635
Schott, W. H., B. D. Haskell, H. M. Tse, M. J. Milton, J. D. Piganelli, C. M. Choisy-Rossi, P. C. Reifsnyder, A. V. Chervonsky, and E. H. Leiter. 200). Caspase-1 Is Not Required for Type 1 Diabetes in the NOD Mouse. Diabetes 53:99. PMID: 14693703
Tse HM, Josephy S, Chan E, Fouts D, Cooper A. 2002. Activation of the Mitogen-Activated Protein Kinase Signaling Pathway is Instrumental in Determining the Ability of Mycobacterium avium to Grow in Murine Macrophages. Journal of Immunology 168:825-833. PMID: 11777978
Tse H, Gill RE. 2002. Bypass of A- and B-Signaling Requirements for Myxococcus xanthus Development by Mutations in spdR. Journal of Bacteriology 184(5):1455-1457. PMID: 11844778
Hager E, Tse H, Gill RE. 2001. Identification and Characterization of spdR mutations that bypass the BsgA protease-dependent regulation of developmental gene expression in Myxococcus xanthus. Molecular Microbiology 39(3):765-780. PMID: 11169116