UAB is the home of several internationally prominent research programs in immunology. The Developmental Immunology Program has traditionally included a basic research program in B cell development and function, together with investigations of primary B and T cell immunodeficiency within the Alabama population. Over the past five years, UAB immunologists led by Dr. Casey Weaver have made seminal discoveries of new T cell subsets, including Th17; adding expertise in T cell development and function to the developmental portfolio.  The Mucosal Immunology program has a tradition of over 25 years of basic investigation uncovering key basic mechanisms in mucosal immunology, and strong translational and clinical research programs on HIV and other vaccines, inflammatory bowel disease and IgA nephropathy. The Arthritis, Autoimmunity, and Rheumatic Diseases Programs have nationally recognized basic research efforts studying the role of death receptors and immunoglobulin Fc receptors as immunoregulatory signals, for investigation of genetic susceptibility to autoimmune disease. A very strong translational and clinical research programs with more than a decade of experience in large-scale clinical trials of immunomodulatory drugs utilizes the UAB CCTS. The Virology and Vaccine Biology Program, coordinated through the Center for AIDS Research (CFAR) and the Departments of Microbiology, Medicine, Pathology, and Pediatrics, has been nationally recognized as a leading basic virology research program.  With its broad local and international clinical and translational research programs that include HIV vaccine development and testing, it has led to the UAB CFAR being internationally recognized as one of the elite AIDS research centers. Newer programs in Cancer Immunology, Allergy, Immunogenetics, Inflammation and Tissue Injury, Transplantation Immunology, Neuroimmunology, and Innate Immunity are poised to become highly competitive.

For details about these UAB research programs, as well as the investigators active in each of these areas, visit the links on the right side bar.