Professor of Microbiology Alexander Rosenberg, Ph.D., will be part of a research team studying T and B tissue-resident memory cells, known as TRM and BRM cells, as part of a five-year, $18.5 million U19 grant awarded to the University of Alabama at Birmingham.

The research grant was awarded to UAB as part of the National Institutes of Health (NIH) program, Cooperative Centers on Human Immunology.

Rosenberg will lead one of the three scientific service cores as part of this research effort. The Rosenberg team will provide analytical expertise in identifying and tracking memory clonal lineages while interrogating the dynamic transcriptional, epigenetic, and phenotypic changes that occur in single cells in the different memory compartments over time.

The research effort will focus on gaining a better understanding of the fundamental processes that regulate BRM and TRM cells, specifically in three unique sites - transplanted lungs, transplanted kidneys and the transplanted uteruses of UAB patients.