Research - News
The regulator HIF1α functions in a cancer-microenvironment that lacks oxygen, and it may be involved in resistance to immune checkpoint blockade therapy.
Results showed longer duration of hypertension is related to higher risk of stroke, higher average systolic blood pressure and a need for more classes of antihypertension medication.
Liou Sun’s research group will seek to understand how ceramides and growth hormone signaling contribute to healthier aging, providing meaningful insights to develop innovative therapies for age-related diseases.
There are no effective antivirals against BK polyomavirus in transplanted kidneys. A better understanding of its replication will offer new ways to protect those kidneys.
This study highlights how high-volume centers, where operators perform these procedures more frequently, achieve better outcomes, including lower 30-day mortality and reduced complication rates.
Heart failure is responsible for 13 percent of deaths worldwide, and half of patients die within 5 years. New therapies are needed.
UAB researchers uncover that interaction between proteins CD2:CD58 can be disrupted to mitigate the expression of genes and proteins that trigger HS pathogenesis.
UAB is combating youth tobacco use with its ninth annual award from the Alabama Department of Public Health.
Funded by the National Institutes of Health, HEALTHe Birmingham will measure the effects of community revitalization on residents’ health.
Preliminary evidence suggests that teletrauma programs are associated with improvements in the quality of initial trauma care, shorter transfer time to advanced trauma centers for severely injured patients and decreased rates of potentially unnecessary transfers to advanced trauma centers, which leads to substantial cost savings.
Safal Khanal will use the grant to lead a clinical trial to investigate the efficacy of a new myopia treatment option.
This polygenic score predicts tamoxifen treatment resistance is better than conventional methods, with potential for personalized medicine application.
Human proteins identified that explain inter-individual differences in functional brain connectivity
This is a step toward an understanding of the brain that ultimately describes the mechanistic basis of human cognition and behavior.
New research finds that a low-carbohydrate diet may improve beta-cell function in people with Type 2 diabetes.
Bacterial viruses, known as phages, are the most abundant biological entities on the planet and are increasingly used as biomedicines to eradicate antibiotic-resistant pathogenic bacteria.
Findings from a new UAB study show greater levels of grandparenting intensity are not associated with greater physical activity.
The National Institute on Drug Abuse award is designed to stimulate innovation and potentially transformative research from early stage investigators.
This investment marks a critical step forward in harnessing cutting-edge technology to revolutionize the accessibility and application of biomedical data science.
UAB researchers explore how polygenic risk scores can refine treatment decisions for patients with high blood pressure.
Results suggest that, rather than stimulating both sides of the brain using DBS, unilateral right DBS may avoid DBS-related declines in verbal fluency and response inhibition in patients with movement disorders like Parkinson’s disease.
UAB awarded more than $11 million to lead study on telehealth options for chronic disease management
A multisite study will compare the effectiveness of telehealth options in patients with a physical disability, Type 2 diabetes and one other chronic health condition.
By showing a critical role for sialylation in the biophysical properties of mucus and mucus transport, the study identifies a possible therapeutic target for the treatment of cystic fibrosis and other muco-obstructive diseases.
The NIH grant will support development of a BionanomatrixTM coating for an aneurysm-therapy flow diverter in the brain.
UAB researchers are pioneering five new projects as they continue making new discoveries and advancing science to benefit oral health locally and globally.
Blazer Bridge Fund provides financial support to innovative ideas and inventions by the UAB community, encouraging advanced discovery.
A cluster analysis in the Deep South showed that racial background significantly influences diabetes subtype distribution.
The study’s findings suggest a combination therapy could be a more effective and a safer approach to treating metastatic colorectal cancer.
Vohra is leading the Center for Additively Manufactured Complex Systems under Extremes at UAB in advancing understanding of 3D-printed materials when subjected to extremes of pressures, temperatures and high-velocity impacts.
A recent study by UAB researchers showed that teenagers with higher levels of adiposity have more cognitive impact from poor sleep compared to teenagers with a healthy weight.
This live biotherapeutic product, tested in mouse models, shows promise in addressing common pathways of lung disease progression.