Jeff Hansen

Jeff Hansen

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Research Editor

jeffhans@uab.edu • (205) 209-2355

Communicates UAB research discoveries and initiatives from across the university for a variety of audiences.

Specific beats include: biochemistry; cell, developmental and integrated biology; microbiology; molecular genetics; neurobiology; pathology; pharmacology and tocixology; Alabama Drug Discovery Alliance; Bill L. Harbert Institute for Innovation and Entrepreneurship.

Björkman will speak on “Structural correlates of antibody neutralization of pathogenic viruses.”
Blacks face much greater rates of heart disease than do whites. A wider study is needed to further investigate this racial difference and identify potential therapeutic targets.
Anindya Dutta, M.D., Ph.D., and colleagues now have detailed the first structure-function study of this long non-coding RNA.
UAB physicians are working on the next steps to begin compassionate or emergency use of the pig kidneys in living humans. Two major approvals will be required.
In response to a viral infection, intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling, leading to different fates for two subsets of those cells — the one producing IL-2 and the one not producing IL-2.
Death or severe brain bleeding in the first week after birth dropped from 27.4 percent to 15 percent after introduction of a bundle of evidence-based, potentially better practices for preterm infants. Median weight of the 820 infants studied was 1 pound, 10 ounces.
The human preclinical model at UAB provides important knowledge before a Phase I clinical trial can begin for living human recipients. Decades of work by researchers across the world preceded UAB’s first clinical-grade pig kidney xenotransplant.

A detailed mechanistic study unravels how the bacterial endotoxin LPS prevents or promotes allergic disease.

Disruption of Blimp1 in regulatory T cells remodels the tumor microenvironment and augments the response to immunotherapy.

Research in animal models shows better formation of the fistulas, which are a lifeline for kidney failure patients as the connection site to dialysis machines.
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