Jeff Hansen

Jeff Hansen

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Research Editor

jeffhans@uab.edu | (205) 209-2355

Communicates UAB research discoveries and initiatives from across the university for a variety of audiences.

Specific beats: 

  • Alabama Drug Discovery Alliance
  • Biochemistry and Molecular Genetics 
  • Biomatrix Engineering and Regenerative Medicine 
  • Cell biology 
  • Center for Biophysical Sciences and Engineering 
  • CCTS
  • Center for Metabolic Bone Disease 
  • Microbiology 
  • Neurobiology 
  • Comprehensive Neuroscience Center 
  • Pathology, research shared with MS2
  • Pharmacology and Toxicology 
  • Physiology and Biophysics 
  • UAB Research Foundation/IIE 
  • Research Administration

Disruption of Blimp1 in regulatory T cells remodels the tumor microenvironment and augments the response to immunotherapy.

Research in animal models shows better formation of the fistulas, which are a lifeline for kidney failure patients as the connection site to dialysis machines.

At UAB, the company IN8bio Inc. is running a Phase I clinical trial to treat glioblastoma multiforme, the most aggressive type of cancer that originates in the brain.

Basic and translational research in this field aims to repair heart injury and prevent the heart failure that often follows a heart attack.

Bacteria use molecular machines to move proteins, including toxins, across cell membranes. M. tuberculosis, which kills more than 1 million people a year, uses the ESX-4 type VII secretion system to transports its potent exotoxin.
Preclinical experiments show how to identify non-responding tumors and improve their response to immunotherapy, using two investigational new drugs that are permitted for human use. Physicians could immediately start investigational research in patients to test the effectiveness of this personalized approach.

The latest grant for Andrea Cherrington, M.D., is $21.7 million over five years from the National Institute on Minority Health and Health Disparities to improve chronic disease outcomes for Black Americans in the Deep South.

The life sciences fund will focus on development of early-stage UAB technologies and startup companies.

Release of TT-10 from nanoparticles improved heart function after a heart attack, accompanied by increased cardiomyocyte proliferation and smaller infarct size.

Lupus, an autoimmune disease that can attack any part of the body, can be confounding because patients often respond differently to the same treatment, and they vary widely in the severity of their symptoms.
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