Research - News
This is the first direct evidence that resident microbiota can have a significant impact on the establishment and pathology of infection by two different human-specific pathogens.
TCE is a known environmental risk factor for parkinsonism. UAB researchers will evaluate whether T cell activation caused by TCE exposure leads to cognitive decline.
Some PD-1+CXCR5+CD4+ T cells will become germinal center-Tfh cells that are essential for B cells to become high-affinity antibody-producing cells. Others do not take that path, instead becoming memory T cells.
The new technology will allow for non-invasive assessments for dry eye disease and inform the development of new treatments.
Periodontal disease is one of the leading causes of tooth loss in adults and may be a risk factor in the development of Alzheimer’s disease.
In a mouse model, border-associated macrophages, not microglia, were essential for the neuroinflammation that precedes neurodegradation. Targeting this subset could be a disease-modifying therapy in neurodegenerative disease.
$46 million awarded by NIH to UAB and partners allows researchers to continue following participants enrolled in the national Multicenter Osteoarthritis Study.
The newly introduced kidney function equation has value in predicting heart failure comparable to the old equation but may reduce racial disparities by improving access to heart failure therapy among Black heart failure patients.
UAB is one of the seven institutions receiving multimillion renewal funding to advance its Cyber Corps program. The grant will support an integrated curriculum for training master’s students in both cybersecurity and artificial intelligence.
New research from UAB shows a possible link between poverty and a child’s possibility of having a relapse in their acute lymphoblastic leukemia.
Published results from two UAB studies found the duration of intermittent hypoxemia events and the presence and persistence of a patent ductus arteriosus after birth are two novel risk factors of BPD-PH in preterm infants.
The UAB study revealed that specific linguistic styles within influencer posts can enhance or diminish engagement with the content.
Earlier research suggests that the use of low-dose atropine drops plays a role in slowing the progression of myopia in children. However, new research co-led by experts in the UAB School of Optometry shows that may not be the case.
The University of Alabama at Birmingham has been awarded $456,786 from the National Science Foundation to fund the development of a 3D-printed high-entropy alloy superconductor.
Despite fewer drivers on the roads and fewer injuries per accident, fatal crashes in Alabama increased by 26 percent over the three years from 2020 through 2022.
Because hypertension and uncontrolled blood pressure are major risk factors for heart disease and stroke, achieving equity in heart and brain health in the United States cannot be reached without paying attention to social determinants of health, a study shows.
These nanowires, which can transport electrons to help a microbe make energy, were first described in a Geobacter bacteria; but now nanowires appear to be widespread in both bacteria and archaea prokaryotes.
This funding will be used to research multiple health conditions, including alcohol-related liver disease, Alzheimer’s disease, breast cancer, heart failure, inflammatory bowel disease and Zhu-Tokita-Takenouchi-Kim syndrome.
UAB researchers conducted a nationwide population-level study to assess the cardiovascular health in Asian American adults. Results revealed that cardiovascular health declined in foreign-born Asian Americans by 28 percent from 2011-2020.
Researchers used a mouse model and cutting-edge neurobiological techniques to show how psychological stress during adolescence alters neuronal functions in the brain, resulting in altered postpartum social behavior.
Findings from an ongoing UAB study suggest obesity is a driving factor in the development of PCOS, the most common endocrine cardiometabolic disorder of women.
Chronic obstructive pulmonary disease patients with type 2 inflammation saw rapid and sustained improvements in their disease after treatment with the monoclonal antibody dupilumab.
The 31 new scholars from 22 U.S. institutions are all outstanding early career faculty in science who have the potential to become leaders in their research fields and advance diversity, equity and inclusion. Each scholar will receive up to $8.6 million over 10 years.
UAB researcher Yusen Zhai, Ph.D., discovered that overall mental health care accessibility took a step forward during the pandemic due to telehealth.
UAB researchers conducted a study including approximately 20,000 left ventricular assist device recipients and found that women had worse clinical outcomes compared with men across social and clinical subgroups of interest.

Results from the Chronic Hypertension and Pregnancy trial found treating preexisting mild chronic hypertension in pregnant women is safe from both the mom and baby. Results published in April 2022 have since led to changes in national guidelines.
The University of Alabama at Birmingham has been awarded $8 million from the United States Department of Energy’s National Nuclear Security Agency.
New study indicates that StreetBit has the potential to save millions of dollars annually and reduce pedestrian injuries by implementing such programs on a larger scale.
UAB was one of four sites leading a clinical trial to evaluate the effectiveness of adding Pembrolizumab to endometrial cancer care.
Knowledge of this previously unrecognized mechanism may aid therapy for patients with interleukin-6 signaling mutations and hyper-IgE Syndrome, or HIES.
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