Research - News
UAB’s Julie Kanter, M.D., says statewide surveillance programs for sickle cell disease can help facilitate progress to improve outcomes.
Preclinical experiments show how to identify non-responding tumors and improve their response to immunotherapy, using two investigational new drugs that are permitted for human use. Physicians could immediately start investigational research in patients to test the effectiveness of this personalized approach.
About three-quarters of people were consistently honest, telling between zero and two lies per day. By contrast, a small subset of people averaged more than six lies per day and accounted for a sizable proportion of the lies, says researcher Timothy Levine, Ph.D.
The grant links researchers from different disciplines, institutions and locations to study basic mechanisms that contribute to Parkinson’s disease.
The effort led by UAB is projected to receive $17 million from NIH to support up to four years of patient follow-up.
The life sciences fund will focus on development of early-stage UAB technologies and startup companies.

Release of TT-10 from nanoparticles improved heart function after a heart attack, accompanied by increased cardiomyocyte proliferation and smaller infarct size.

The collaboration puts UAB experts on the ground in Zambia to strengthen research and public health capacity and address major global health challenges.
UAB researchers will study psilocybin, a psychedelic compound, on its effects on smoking cessation.

The NIH grant creates Multiple Chronic Disease Centers around the nation to target chronic disease in minority populations.

Lupus, an autoimmune disease that can attack any part of the body, can be confounding because patients often respond differently to the same treatment, and they vary widely in the severity of their symptoms.
The new grant links UAB researchers with colleagues at two other institutions to search for ways to advance therapies from bench to bedside.
The K23 research project focuses on the adaptation of a behavioral physical activity intervention with peer support for women with HIV and co-occurring hypertension. 
New study from UAB women’s health, infectious diseases and pediatric experts show increase in morbidity and adverse outcomes in pregnant patients caused by the Delta variant.
The O’Neal Invests program funds UAB investigators starting new cancer-related projects to initiate key, preliminary work needed to enable competitive R01 applications from the NIH.
UAB public health researcher suggests new framework in tracking tobacco and nicotine use in adolescents in the United States.

Fecal-dominant donor microbes in the recipient patients after fecal microbe transplantation did not correlate with response to anti-PD-1 therapy.

The study, from UAB’s Institute for Arts in Medicine, shows that learning tricks in a magic camp can boost feelings of self-esteem and confidence in children and adolescents with disabilities.

Blood and marrow transplantation strategies have changed significantly over the past four decades; but recipients still experience excess mortality that translates into 8.7 years of life lost, according to researchers in UAB’s Institute for Cancer Outcomes and Survivorship.

NCHPAD will utilize the grant, the largest in the history of the UAB School of Health Professions, to expand its role as a knowledge translation and implementation science/evaluation center to promote access to health and wellness programs for people with disabilities across the nation.

The study, led by Barbara Gower, Ph.D., is the first randomized clinical trial of a hypothesis that reducing fat stored around organs, through diet alone, can rescue beta-cell function.

Limiting neuroinflammation may represent a promising new approach to treat neurological diseases driven by neuroinflammation, such as stroke, spinal cord injury and neuropathic pain.
Researchers are looking for people who either have Type 2 diabetes or are overweight to participate in the studies.
A study conducted by UAB researchers found that insulin resistance, a precursor to fatal cardiovascular events, is common among young adults.
UAB’s Technology Innovation Center houses a state-of-the-art data center, the fastest university internet connectivity in the state, expandable technology infrastructure, and colocation for UAB’s partners in distributed IT.  
The grant will explore ways to employ artificial intelligence with telehealth in rural, underserved areas of the South.

The higher infectivity correlates with mutations that increase viral binding to a cell surface glucosaminoglycan, heparan sulfate.

Pharmacogenomics has become a valuable tool for optimizing treatments and is poised to play an increasing role in clinical care.

This finding upends the long-held paradigm that priming during lung infections takes place only in the draining lymph nodes, and it will be key to developing more efficient vaccinations and therapies for respiratory challenges.

Christine Curcio, Ph.D., says research findings are important in suggesting that treatments already investigated for cancer might be beneficial for AMD.
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