You may be eligible to take part in this study if you have previously had a heart attack (myocardial infarction) or brain attack (stroke) or have been diagnosed with poor circulation. If you have reduced kidney function or if you have inflammation in your blood vessels ? The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a 4 year research study to look if an investigational medicine ,called ‘ziltivekimab’ can be used to treat people with cardiovascular disease, chronic kidney disease and inflammation. Qualified participants will receive study drug at no cost and may be compensated for time and travel. For more information, and to see if you might be eligible to join, contact (205) 996-4015 or email at ccnrn@uab.edu.