The Reporter

Struggling to find an effective depression treatment?

If you are currently taking antidepressant medications but still struggle with depression, you may qualify for a new clinical research study. The study is evaluating an oral investigational medication for depression that can be taken with your current antidepressant medication. For more information and to see if you're eligible to participate, please call 205-975-8542 or 205-934-2484.

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Adolescent Depression Study

Are you or is your child...
- Between the ages of 11 and 19?
- Feeling sad, down, or hopeless?
- Feeling guilty, tense, or irritable?

If so, you may be eligible to participate in a non-treatment research study.
Compensation provided for both parent and child, if applicable.
For more information, please contact the UAB Office of Psychiatric Clinical Research at (205) 934-2484.
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We Need Healthy Adolescent Controls!
- Are you in good physical health?
- Are you between the ages of 11 and 19?
- Do you have NO history of Depression?

If so, you may be eligible to participate in a non-treatment research study.
Compensation provided for both parent and child, if applicable.
For more information, please contact the UAB Office of Psychiatric Clinical Research at (205) 934-2484.

Published in Clinical Trials

We Need Healthy Controls!

Are you between the ages of 18 and 60?
Do you have NO history of Depression?
Are you eager to participate in research?

If so, you maybe be eligible to participate in a non-treatment study. Compensation provided.

For more information, please call the UAB Office of Psychiatric Research at (205) 934-2484.

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ADAPT: A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse

Opportunity to quit smoking cigarettes. Fully remote surveys.

If you smoke cigarettes every day, you may be eligible for a research study with the University of Alabama at Birmingham. The research study involves initial online screening, 8 contacts over 6 months and a chance to try varenicline, a prescription smoking cessation medication, or nicotine patches and lozenges. Compensation is available for those who are eligible and participate. Please follow the link below for more information and to see if you are eligible:

https://redcap.musc.edu/surveys/?s=8JWFT9XFY3FYR7Y3

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Participants ages 35-65 needed. Compensation up to $310.

Participants between the ages of 35 and 65 are needed for this study. The purpose of the study is to fill in what we don’t know about how schizophrenia affects people as they get older. We want to find out what we can do to help older individuals with schizophrenia live better lives. The study includes 4 visits over the course of two weeks. The screening visit will take 2 hours. The first study visit will take 3 hours. The second study visit will take 2 hours. The third study visit will take 9 hours. This study will include: a clinical interview, cognitive batteries, questionnaires and assessments related to your daily and psychiatric functioning, two 90 minute MRI scans of your brain, a fasting blood draw, and a urine drug screen and pregnancy test (for females). Compensation is up to $310. TO SEE IF YOU QUALIFY PLEASE CONTACT (205) 934-8203.

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Diagnosed with depression? Your mental health matters.

If you’ve been feeling stuck and longing for relief, you may be eligible to receive dedicated medical attention, an investigational therapeutic and compensation for your involvement in an innovative research study.

We're conducting clinical research in depression to learn how individuals’ brain biology impacts response to treatment, with the goal to help people find relief faster. You do not need to already have a diagnosis to participate.

If you’re currently taking medication, you are likely still eligible for our studies and don’t have to stop your existing treatment regimen.

For more information about this trial and to see if you qualify, please contact Kristine at kristinepike@uabmc.edu or 205-975-8542.

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Are you currently or have you ever been depressed?

Major Depressive Disorder is a mental health condition characterized by periods of low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. The purpose of this clinical research study is to evaluate the safety and effectiveness of an investigational drug for Major Depressive Disorder, also known as Major Depression. Study participation may include several clinic visits over a period of up to 5 months with an opportunity to conduct some visits either virtually or in-clinic. Qualified participants will receive compensation for their time.

For more information about this trial and to see if you qualify, please contact Kristine at kristinepike@uabmc.edu or 205-975-8542.

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Project ATHENA: Integrated e-Health (Electronic Health) for HIV Prevention and Substance Use Disorders in Justice Involved Women

Are you:
• A woman on parole, probation, or recently released from prison or jail?
• A woman who has used drugs?
• Interested in learning about a way to protect yourself against HIV?

You may qualify for a paid research study at the University of Alabama at Birmingham, in partnership with Yale University.
• Participate in confidential study interviews at our research office.
• Earn $50 for each interview, up to $225 for participating in the study.

Fill out our contact survey at: https://yalesurvey.ca1.qualtrics.com/jfe/form/SV_d7sAjr6GDsjiJng?Q_CHL=qr

Or you may call: (205) 934-2851 or Email: AthenaStudy@uabmc.edu

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Cigarette Smokers: Interested in a novel research approach to quitting smoking at no cost to you?

University of Alabama at Birmingham is seeking cigarette smokers who would like to quit smoking for participation in a scientific research study. The research study involves free counseling and treatment provided in a comfortable, supportive setting. The study may involve ingestion of psilocybin, a psychoactive substance found in psychedelic mushrooms that have been used as a sacrament in various cultures. Some research studies have suggested that psychedelics, when administered under interpersonally supportive and well-prepared conditions, may be effective in helping people overcome addictions.

Questionnaires, interviews, and biological measures of smoking will be used to assess the treatment's effects on mood and smoking. Participants will be compensated $50 per session. If you would like to discuss the possibility of volunteering, please call 205-996-1198, or go to www.quitsmokingbaltimore.org for more information about the study and to complete the online study prescreener for the UAB site. Confidentiality will be maintained for all applicants and participants.

Volunteers must be 21 years of age or older, and must live within travel distance of the study site in Birmingham.

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Ongoing Treatment Resistant Depression study

There is an ongoing psychedelic clinical research study evaluating the safety and efficacy of an intranasal study drug for patients with treatment resistant depression.

To qualify patients need to be 18-75 years of age, failed to respond to an adequate dose & duration of at least 2 medicines for depression. If currently taking antidepressants, willing and able to discontinue.

If eligible, study participants will be expected to abstain from illicit drugs for the duration of the trial & attend all study visits & follow instructions from the study doctor. Study examinations will be at no cost to you.

For more information please contact 205-996-1198 or spremani@uab.edu

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Healthy Participants Needed: Cognition Across the Lifespan in Mental Illness

Healthy participants needed if you are:

18-75 years old
No diagnosis of any neurological disorders or psychiatric problems
No history of problematic drug/alcohol use in the last 3 months

For more information and to determine eligibility, please call the Neuroscience Laboratory of Social Behavior at (205) 934-8203 or email nlsb.uab@gmail.com.
**Compensation is provided**

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SAVITRI Study for Depression

If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.

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Do you sometimes feel hopeless, or that life has no purpose?

UAB researchers are looking for adults (ages 25-65) who are suffering from demoralization - feelings of hopelessness or meaninglessness - to participate in a research study evaluating a novel medication.

To see if you qualify call 205-379-7527.

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CURB-2 Trial: We are currently recruiting adults who use cocaine and are interested in participating in a study to examine medications as a possible treatment for cocaine use disorder.

CURB-2 is an abbreviation we use to refer to this study because there was a similar study completed and published in 2016 called CURB, which stands for Cocaine Use Reduction with Buprenorphine. The results from that study showed that using injectable naltrexone and sublingual buprenorphine was beneficial to participants on high doses of the medication. This study will give injectable naltrexone and injectable buprenorphine to make sure medication doses are consistent to confirm potential benefits.

There are no approved treatments specifically for cocaine use disorder. We are looking for adults (18-65 years of age) who are using cocaine and who are interested in reducing or stopping their use. The purpose of our study is to test a combination of two medications for 2 months as a possible treatment for cocaine use disorder.

This study includes the use of a placebo, which looks like the medication we are testing but does not include any active medicine. Study medication and assessments will be provided to participants at no cost. Participants will receive compensation for their time and efforts.

Study information will be kept strictly confidential. Your privacy is important to us.

Call us for more information at 205-996-0211 or email us at curb2study@uabmc.edu

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LGBTQ+ Cancer Well-Being Study

Do you identify as an individual living with cancer and part of the LGBTQIA+ community or a care partner of someone in this community? A research lab at the University of Alabama at Birmingham is looking to learn about the day-to-day experiences of LGBTQIA+ cancer survivors and their care partners. We are interested in how individuals manage difficult situations related to their respective roles in their relationships. Individuals living with cancer often encounter stressful situations that can impact their mood and any additional stressors from living as a sexual or gender minority with a lack of resources adds an increased risk of experiencing stressful situations. The goal of this work is to develop resources that better support the well-being of LGBTQIA+ individuals living with cancer and their care partners. This study will take place FULLY online with completion of daily surveys. All participants will be compensated. To learn more about our study contact us at starlab@uab.edu

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Hispanic Dementia Caregiver Well-Being Study

The University of Alabama at Birmingham (UAB) is inviting Hispanic or Latino/a family caregivers to complete short surveys for our study. Your answers will help us understand your daily experiences and develop services to better support caregivers in the community. You will be paid for your time. Your answers will remain anonymous. To learn more contact us at starlab@uab.edu or call Lorelí Alvarez at 205-996-0339.
To be contacted by the research team register here: https://uab.co1.qualtrics.com/jfe/form/SV_d3TmeAlFEPBRmNU

¿Cuidas de un familiar con problemas de memoria o demencia/enfermedad de Alzheimer?
La Universidad de Alabama en Birmingham (UAB) está invitando a cuidadores familiares hispanos y latinos para que completen breves encuestas para nuestro proyecto. Tus respuestas ayudarán a comprender mejor las experiencias del día a día y a desarrollar servicios para apoyar mejor a los cuidadores familiares de la comunidad. Les compensaremos por su participación. Sus respuestas permanecerán anónimas. Para saber más escribe a starlab@uab.edu o llama por teléfono al 205-996-0339 y pregunta por Lorelí Alvarez.
Para ser contactado por el equipo de investigación haga click aquí: https://uab.co1.qualtrics.com/jfe/form/SV_d3TmeAlFEPBRmNU

Published in Clinical Trials

SAVITRI Study for Depression

If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.

Published in Clinical Trials

Alzheimer’s Dementia and Agitation Clinical Study

Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.

Published in Clinical Trials

SAVITRI Study for Depression

If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.

Published in Clinical Trials

Alzheimer’s Dementia and Agitation Clinical Study

Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.

Published in Clinical Trials

Participate in this study on major depressive disorder

You may be able to participate in this study if you: are 18 years of age or older, have been diagnosed with major depressive disorder, MDD, have not adequately responded to at least 1 different antidepressant treatment, and are currently on an antidepressant treatment. Please leave a voice message at (205) 975-0068 or email candacegreen@uabmc.edu for more information.

Published in Clinical Trials

SAVITRI Study for Depression

If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.

Published in Clinical Trials

Are you an African American or Caucasian with Opioid Use Disorder?

We are enrolling opioid users without a history of psychosis, endocrine diseases, inflammatory diseases, or autoimmune diseases. If you meet these criteria you may be eligible to participate in a research study. Compensation provided up to $20. For more information, please call the UAB Office of Psychiatric Research at 205-934-8336.

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Do you have ADHD and use stimulant medication?

We are looking for adults between 21-55 years old and diagnosed with Attention Deficit and Hyperactivity Disorder (ADHD), and use stimulant medication to participate in our study. We want to determine the role of ADHD stimulant medication on balance and other factors, such as physical activity in improving balance performance. We hypothesize that ADHD will improve balance performance in adults with ADHD. We also hypothesize that moderate to vigorous physical activity behaviors will positively influence balance performance in this population. Participants will be required to make two visits. Once on-medication; and on the second visit, we will ask participants to forgo ADHD medication 24 hours before the testing. For more information please contact Mansour at (205) 503-2977, or by email at amansour@uab.edu.

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Participants with depression ages 18 and older needed for RECOVER study

The RECOVER study will investigate the use of Vagus Nerve Stimulation (VNS) Therapy in up to 1,000 people across the United States. To join the RECOVER study you must be 18 years or older and: currently depressed, have bi-polar depression that has lasted for at least two years or recurred several times, and have tried at least four types of antidepressant treatments and not found them helpful. Please leave a voice message at (205) 975-0068 or email candacegreen@uabmc.edu for more information.

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Displaying items by tag: mental health and psychiatry