In order to assure excellence in the protection of human research participants, the IRB submission and review process, and training and mentorship in the conduct of human subjects research, Trainees will no longer be permitted to serve as Principal Investigator on IRB submissions effective April 1, 2025.
Key Changes:
- Principal Investigator Requirements: Trainees, including students (undergraduate, graduate, and professional), residents, interns, postdoctoral trainees, and medical fellows are no longer permitted to serve as Principal Investigator for projects involving human subjects research.
Individuals serving as PI on an IRB submission must meet criteria in the UAB policy "Definition of a Principal Investigator".
- Trainee personnel roles: Trainees who will be engaged in human subjects research must generally be listed as a Subinvestigator or Other Personnel on the IRB submission.
- Preparation & Submission of Applications: Those in a Subinvestigator or Other Personnel role may initiate and draft submissions. However, the Principal Investigator/Faculty Mentor must submit after thoroughly reviewing the application for quality and accuracy. All communications from the Office of the IRB will be sent to the PI.
These changes will strengthen our research practices and provide better support for our trainees. For more information on this change, please refer to the Office of Research Position Statement. Additional tools, guidance, and FAQs are being developed and will be available in advance of April 1, 2025.
If you have any questions or need further clarification, please contact Christina Blackmon (