Two positions are available:
- Instructor or Scientist 1 or Researcher IV / lab manager;
- Postdoc position.
We are a collegial and diverse group working on exciting research areas integrating autophagy, metabolism, and redox signaling in cardiovascular and Alzheimer’s disease in the Department of Pathology, with associations with the Center for Free Radical Biology, The Integrative Center for Aging Research, Alzheimer’s disease Center, Center for Neurodegeneration and Experimental Therapeutics, Nutrition Obesity Research Center, and the Comprehensive Cardiovascular Center, at the University of Alabama at Birmingham. We have a strong track record in publications of our research, and a collaborative and collegial atmosphere.
The current work focus on neurodegenerative and cardiovascular diseases with both novel hypotheses of molecular mechanisms, and translational potential. Furthermore, we are interested in integrated approaches and omics/informatics data analyses that may lead to novel hypothesis and directions of translational potential. Our current expertise includes autophagy, mitophagy, lysosomal function, mitochondrial bioenergetics, circadian biology, redox biology, and protein post-translational modifications, as well as microscopy /mouse genetics and behavior/biochemistry techniques. We also believe that we can adopt any new techniques should we need them. We support people as individuals and their unique career development plans.
The initial appointment will be for one year with the possibility of extension contingent on satisfactory performance. Salary will follow NIH guidelines commensurate with training and experience.
Candidates enthusiastic about biomedical science are encouraged to apply. The successful candidate should have strong motivation, good technical and communication skills, meticulous work habits and record-keeping, and the ability to work both independently and in a team.
- Acute inhibition of OGA sex-dependently alters the networks associated with bioenergetics, autophagy, and neurodegeneration, 2022
- Optimization of measurement of mitochondrial electron transport activity in postmortem human brain samples and measurement of susceptibility to rotenone and 4-hydroxynonenal …, 2022
- Differential effects of 2-deoxyglucose and glucose deprivation on 4-hydroxynonenal dependent mitochondrial dysfunction in primary neurons, 2022
- Targeting whole body metabolism and mitochondrial bioenergetics in the drug development for Alzheimer’s disease, 2021
- Mitochondrial Morphology and Mitophagy in Heart Diseases: Qualitative and Quantitative Analyses Using Transmission Electron Microscopy, 2021
- Defining the dynamic regulation of O-GlcNAc proteome in the mouse cortex---The O-GlcNAcylation of synaptic and trafficking proteins related to neurodegenerative diseases, 2021
- New Insights into the Biology of Protein O-GlcNAcylation: Approaches and Observations, 2021
- The promise of a golden era for exploring the frontiers of aging, metabolism and redox biology, 2021
Interested candidates should submit a CV, a cover letter detailing research experience, career plan, and contact details of three references to:
Jianhua Zhang, PhD
Department of Pathology
The University of Alabama at Birmingham (UAB)
Email:
https://sites.uab.edu/jianhuazhanglab/
Jianhua Zhang - Google Scholar
The University of Alabama at Birmingham is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 250 postdocs are training currently in a variety of disciplines, including but not limited to engineering, medicine, natural sciences & mathematics, public health, and optometry.
The UAB Office of Postdoctoral Education and the UAB Postdoc Association work together to develop career opportunities that enhance and define the training experience for all postdoctoral scholars at UAB.
Because of its commitment to the success of postdoctoral fellows, UAB ranks consistently as one of the top locations among US universities for training postdoctoral scholars.