Recent and Selected Publications (from complete bibliography): Patel P, Kearney JF. Immunological Outcomes of Antibody Binding to Glycans Shared between Microorganisms and Mammals. Journal of Immunology 2016 Dec 1;197(11):4201-4209. Review. Abstract Patel PS, King RG, Kearney JF. Pulmonary α-1,3-Glucan-Specific IgA-Secreting B Cells Suppress the Development of Cockroach Allergy. Journal of Immunology 2016 Oct 15;197(8):3175-3187. Erratum in: Journal of Immunology 2016 Dec 15;197(12 ):4861. Abstract New,
J.S., King, R.G., and Kearney, J.F. Manipulation
of the glycan-specific natural antibody repertoire for
immunotherapy. Immunological
Reviews: 2016; 270(1): 32-50. Abstract Patel,
P.S. and Kearney, J.F. Neonatal
exposure to pneumococcal phosphorylcholine modulates the development of
house dust mite allergy during adult life. Journal of Immunology: 2015;
194(12): 5838-50. Abstract Wharton,
R.E., Stefanov, E.K., King, R.G., and Kearney, J.F. Antibodies
generated against Streptococci protect in a mouse model of disemminated
aspergillosis. Journal of
Immunology: 2015; 194(9): 4387-96. Abstract Kearney,
J.F., Patel, P., Stefanov, E.K., King, R.G. Natural antibody
repertoires: development and functional role in inhibiting allergic
airway disease. Annual Review
of Immunology: 2015; 33:475-504. Abstract Vale,
A.M., Kapoor, P., Skibinski, G.A.,
Elgavish, A., Mahmoud, T.I., Zemlin, C., Zemlin, M., Burrows, P.D.,
Nobrega, A., Kearney, J.F., Briles, D.E., Schroeder, H.W., Jr. The link between
antibodies to OxLDL and natural protection against pneumococci depends
on D(H) gene conservation. The
Journal of Experimental Medicine: 2013; 210(5):875-90.
Abstract Kin,
N.W., Stefanov, E.K., Dizon, B.L.P., Kearney, J.F. Antibodies generated
against conserved antigens expressed by bacteria and allergen-bearing
fungi suppress airway disease. J Immunol: 2012 Sep 1; 189
(5), 2246-2256. Abstract Foote,
J.B., Mahmoud, T.I., Vale, A.M., Kearney, J.F. Long-term maintenance
of polysaccharide-specific antibodies by IgM-secreting cells. J Immunol: 2012 Jan 1; 188(1):
57-67. Epub 2011 Nov 23. Abstract Mahmoud,
T.I., Schroeder, H.W., Jr., Kearney, J.F. Limiting CDR-H3
diversity abrogates the antibody response to the bacterial
polysaccharide alpha-1,3 dextran. J Immunol: 2011 Jul 15; 187(2):
879-86. Epub 2011 Jun 15. Abstract Mahmoud, T.I., Kearney, J.F. Terminal deoxynucleotidyl transferase is required for an optimal response to the polysaccharide alpha-1,3 dextran. J Immunol: 2010 Jan 15;184(2):851-8. Epub 2009 Dec 16. Abstract Balazs, M., Martin, F., Zhou, T., and Kearney, J.F. Blood dendritic cells interact with splenic mariginal zone B cells to initiate T-independent immune responses. Immunity 17(3):341-52, Sep, 2002. Abstract Martin, F. and Kearney, J.F. Marginal-zone B cells. Nature Reviews Immunology 2(5):323-35, May 2002. Abstract Thai, T.H., Purugganan, M.M., Roth, D.B., and Kearney, J.F. Distinct and opposite diversifying activities of terminal transferase splice variants. Nat. Immunol. 3(5):457-62, May 2002. Abstract Benedict, C.L., Gilfillan, S., and Kearney, J.F. The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform. J. Exp. Med. 193:89-99, 2001. Abstract Martin, F., Oliver, A.M., and Kearney, J.F. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14:617-629, 2001. Abstract Martin, F. and Kearney, J.F. Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk. Immunity 12(1):39-49, 2000. Abstract Benedict, C.L. and Kearney, J.F. Increased junctional diversity in fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice. Immunity 10:607-617, 1999. Abstract |