2002 UAB Botanicals Workshop

Purdue-UAB Botanicals Center for Dietary Supplements Research
2002 UAB Botanicals Workshop
September 9-10th, 2002
University of Alabama at Birmingham

Modern research on the use of botanicals in dietary supplements in treating chronic disease depends heavily on being able to assess the quality of the dietary supplements as well as the biochemical and physiological effects in the host. Mass spectrometry has an important role in achieving each of these objectives. It enables careful evaluation of the chemical composition (both qualitative and quantitative) of the dietary supplements. It also can be used to establish how the compounds in the supplements are absorbed into the body and in what chemical forms they circulate. And mass spectrometry is at the forefront of the rapidly emerging field of proteomics, where the effect of the botanicals on physiological protein targets - receptors, growth factors, enzymes, structural proteins, etc. - can be assessed by enabling identification of proteins that undergo differential expression, or enabling identification and analysis of any alterations in modifications.

The goal of the 2002 UAB Botanicals Workshop was to introduce investigators, postdocs, and students to concepts and techniques in mass spectrometry and proteomics that apply to research on botanicals and dietary supplements.

These files are PDF and opens with Acrobat Reader.

1. Front Page
   
   
2. Workshop Faculty
   
   
3. Course Details
   
   
4. Opening Comments
   
   
5. Basics of Mass Spectrometry
   
   1. Electrospray and sample Extraction
      
   2. MALDI
      
      
6. MS of polyphenols
   
   1. Tandem MS of polyphenols
      
   2. Nano MS of polyphenols
      
      
7. Proteomics
   
   1. 2-D analysis
      
   2. Peptide Fingerprinting
      
   3. LC-MS-MS of peptides
      
   4. Bioinformatics
      
      
8. Participants Photo