New Institutional Research Cores Named
The Office of Research and the Institutional Research Core Program (IRCP) is pleased to announce fifteen cores to be included as part of the IRCP. Click here for more information.
Advanced Materials Characterization Core
The AMCC has a wide range of equipment to serve the UAB community and external educational institutions. In addition, we provide equipment usage to a variety of different industries.
Animal Behavioral Assessment Core
The Behavioral Assessment Core provides a facility for the behavioral testing of mice and rats. Newly created transgenic mice can be analyzed using the most-accepted battery of behavioral tests, the SHIRPA (Rogers et al. 1997).
Bio-Analytical Redox Biology (BARB) Core
The BARB Core provides state-of-the-art services in mitochondrial metabolism, oxidative stress, psychological and physiological stress assessment research on a fee-for-service basis.
UAB Biological Data Science Core (U-BDS)
The UAB Biological Data Science Core (U-BDS) offers access to computational biology capabilities.
This newly founded Institutional Research Core provides services supported by Masters and Ph.D. level scientists who are experts in Computational Biology and Biomedical Data Sciences.
Cryo-Electron Microscopy Facility
The Cryo-Electron Microscopy Facility (CEMF) advances the overall UAB mission by supporting the application of cryo-EM in making new scientific discoveries. We provide access and training in the use of cutting edge cryo-EM technology and techniques for the characterization of biological samples from the cellular to the atomic scale.
Flow Cytometry and Single Cell Core Facility
Comprehensive Flow Cytometry Facility provides state-of-the-art equipment and services for UAB investigators to advance basic and clinical research.
Genomics Core Laboratories
The Genomics Core Laboratory has the capability of performing standard fluorescent and Next-Generation Sequencing (NGS), high and low throughput custom genotyping from 1 SNP to more than 5 million SNPs.
High Resolution Imaging Facility
The High Resolution Imaging Facility (HRIF) provides state-of-the-art imaging resources and technical support to the UAB community.
Human Imaging Shared Facility
The Human Imaging Shared Facility (HISF) provides advanced medical imaging resources and services in support of campus wide research, including the O’Neal Cancer Center clinical studies.
Macromolecular Structure Core
Cryo-EM and X-ray crystallography are complementary techniques that work in concert to resolve mechanistic aspects of biological processes. The MSC addresses the needs of investigators for both XRC and Cryo-EM in one unified core facility.
Mass Spectrometry / Proteomics Shared Facility
Mass Spectrometry/Proteomics Shared Facility provide state-of-the-art capabilities and training in mass spectrometry, proteomics, and bioanalytic technologies to support the research needs of UAB Cancer Center members.
Metabolism Core
Metabolism Core provide state-of-the-art assessments of human energy expenditure, substrate metabolism, body composition, body fat distribution, and bone quality.
Microbiome Core
The UAB Microbiome Core provides 16S rRNA gene sequencing of fecal and other biological samples for microbiome analysis.
MMR-CBPR-QR
The Mixed Methods Research-Community Based Participatory Research-Qualitative Research Approaches (MMR-CBPR-QR) Core was developed following the increase in recognition of these approaches in social and behavioral sciences, and in the increased calls by funders for research using these methodologies.
Nuclear Magnetic Resonance
The NMR Facility consists of seven NMR spectrometers located in six research laboratories in UAB’s Department of Chemistry building. The facility is designed to allow researchers direct 24/7 access to all spectrometers. It also provides NMR expertise for researchers needing NMR data through submitted samples, either on a service basis or as part of a collaborative research project.
Preclinical Imaging Shared Facility
The Preclinical Imaging Shared Facility supports multimodality imaging in preclinical models to accelerate the translation of basic research to human trials. Imaging conducted in the facility currently provides rapid, repeated, accurate, and cost-effective evaluation of new cancer treatments in preclinical models, using the most sophisticated technologies available.
Research MRI Core
Research MRI provides resource at UAB for state-of-the-art MRI neuroimaging experiments and analyses for examining brain and body anatomy and function both in health and disease.
Small Animal Imaging Shared Facility (SAIF)
SAIF provides a multimodality imaging approach to provide a molecular understanding of disease processes in animal models, allows for therapeutic assessment of response, supports the development of novel imaging contrast agents, and facilitates translational preclinical imaging studies precluding clinical trials.
Social Determinants of Health (SDH) Core
The Social Determinants of Health (SDH) Core enables UAB investigators to measure the effect of social and environmental risks for disease etiology, progression, management, and outcomes, and test interventions that ameliorate their effect.
Transgenic & Genetically Engineered Models Core (TGEM)
UAB Transgenic & Genetically Engineered Models Core include the production of mouse models using gene targeting and DNA and ES cell injection methods. Our most recent service is in creating gene knockouts using the TALEN and CRISPR/Cas9 nucleases in mice, rats and zebrafish.
