The center is comprised of four research units: the Clinical Trials Unit, the Trauma Care Delivery Research Unit and the Basic Science and Translational Research Unit.
| Trauma Resuscitation with Group O Whole Blood Or Products (TROOP) Trial |
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| Lead Institution: | University of Alabama at Birmingham |
| Principal Investigator: | Jansen/Hurst |
| Status: | Enrolling |
| Description: | Prospective, multicenter, parallel-group, randomized clinical trial comparing whole blood and component therapy in the resuscitation of trauma patients with life-threatening hemorrhage. |
| Funder: | NHLBI |
| Clinicaltrials.gov Link: | https://clinicaltrials.gov/study/NCT05638581 |
| Additional details: | https://sites.uab.edu/troop/uab-home/ |
| Publications: | |
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| Trauma and Prothrombin Complex Concentrate (TAP) Trial |
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| Lead Institution: | University of Alabama at Birmingham |
| Principal Investigator: | Jansen/Cox |
| Status: | Closed |
| Description: | Prospective, multicenter, randomized, double-blind, placebo controlled, parallel-group, large simple trial to investigate the efficacy and safety of a single intravenous infusion of KCentra/Beriplex in patients with traumatic injury and confirmed or suspected acute major bleeding predicted to receive a large volume blood product transfusion. |
| Funder: | CSL Behring |
| Clinicaltrials.gov Link: | https://clinicaltrials.gov/study/NCT05568888 |
| Additional details: | xxx |
| Publications: | https://pubmed.ncbi.nlm.nih.gov/39787574/ |
| https://pubmed.ncbi.nlm.nih.gov/38959020/ | |