Explore UAB

Evelyn F. McKnight Brain Institute

Arrant Lab

The Arrant Lab's goal is to investigate the cellular mechanisms underlying functional deficits in dementia and aging. We seek to integrate data from cellular and animal models with data from patients to gain insight into mechanisms of disease and discover new therapeutic targets.

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Day Lab

The Day Lab's goal is to understand how experience alters the brain, and how those changes drive future behaviors. We approach this broad topic at diverse levels of analysis that integrate molecular, genetic, and epigenetic tools with techniques that probe the function of single neurons and entire neuronal circuits.

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De Miranda Lab

The lab's research is focused on the environmental influence on neurologic disease and neurodegeneration.

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Goldberg Lab

The Goldberg Lab is an outstanding training environment for students, postdocs and other lab members to collectively achieve the overall research mission, which is to understand how genetic mutations cause inherited forms of Parkinson’s disease (PD).

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Gray Lab

The overall mission of the Gray Lab is to identify and understand the underlying mechanisms that contribute to cellular dysfunction and neurodegeneration in Huntington’s Disease and X-linked Dystonia Parkinsonism.

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Hernandez Aging and Cerebral Health Neuroscience (ACHN) Lab

A lab group researching the neuroscience of cognitive aging and neurodegeneration.

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Herskowitz Lab

The Herskowitz Lab conducts research on Alzheimer’s disease (AD) and Frontotemporal dementia (FTD) and is committed to identifying better therapeutic targets and finding more effective treatments for these devastating disorders.

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K.M. Costa Lab

The Costa Lab uses theory-inspired behavioral tasks, in combination with several cutting-edge methods for recording and manipulating brain activity, to explore how animals integrate new information with previous knowledge to guide behavior.

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Knight Neuroimaging Lab

The lab’s research is focused on better understanding the neural systems that mediate learning, memory, and emotion processes.

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Lazar Lab

The Lazar research team has broad interests in aging and vascular disease, with an emphasis on reversible causes of cognitive decline, risk-factor modification to promote brain health, and recovery after stroke.

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Lee Lab, The UAB Neuroscience Laboratory of Social Behavior

The lab aims to understand cross-diagnostic mechanisms of poor social functioning which can be linked to underlying pathophysiological processes and may, in turn, lead to the development of effective treatments for social dysfunction.

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Lubin Lab

The Lubin Lab's research is focused on understanding the cellular and molecular mechanisms underlying transcriptional regulation of genes in the nervous system to mediate cognition and how these mechanisms are altered with aging and cognitive disorders including epilepsy and Alzheimer's disease.

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Lucas Lab

Research in the Lucas Lab is driven by a passion to improve the lives of people with mental illness. We conduct preclinical research in mouse models to understand the mechanisms underlying susceptibility to psychiatric illness, with an emphasis on sex as a biological factor.

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Roberson Lab

The Roberson Lab's mission is to understand the neurobiology of age-related conditions affecting cognition, including Alzheimer's disease, frontotemporal dementia, and cognitive aging, and to contribute to developing new treatments for these conditions.

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Standaert Lab

The main objective of the Standaert Lab is to address the role of genetic and epigenetic factors in Levodopa induced dyskinesia.

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Tyrrell Lab

Most chronic diseases occur at older ages in people, yet most disease models rely on young animals. The Tyrrell lab studies aging specific disease mechanisms by modeling chronic inflammatory diseases using old mice. They use cutting edge molecular biology, immunology, and genetic approaches including flow cytometry, imaging, and single-cell RNA sequencing.

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Ubogu Lab

The Neuromuscular Immunopathology Research Laboratory (NIRL) is a translational basic science research laboratory dedicated to understanding the pathogenesis of immune-mediated disorders of the peripheral nervous system, with specific emphasis on peripheral neuroinflammation, and the biology of blood-nerve barrier in health and disease, including chronic neuropathic pain.

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Visscher Lab

The Visscher Lab studies human behavior and brain activity using precise behavioral measurements (including psychophysics and tracking of eye movement), functional magnetic resonance imaging (fMRI) and electroencephalography (EEG).

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Wadiche Laboratories of Synaptic Physiology

Research in the labs of Linda Overstreet-Wadiche and Jacques Wadiche focuses on studying the function and regulation of synaptic transmission.

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Zhang Lab

The Jianhua Zhang Lab focuses on the redox, metabolic and interactome regulatory mechanisms on autophagy, mitophagy and endolyosomal functions, as novel insights are laying the foundation for treatment of Parkinson’s, Alzheimer’s, cardiovascular and inflammatory diseases.

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