Jeff Hansen

Jeff Hansen

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Research Editor

jeffhans@uab.edu | (205) 209-2355

Communicates UAB research discoveries and initiatives from across the university for a variety of audiences.

Specific beats: 

  • Alabama Drug Discovery Alliance
  • Biochemistry and Molecular Genetics 
  • Biomatrix Engineering and Regenerative Medicine 
  • Cell biology 
  • Center for Biophysical Sciences and Engineering 
  • CCTS
  • Center for Metabolic Bone Disease 
  • Microbiology 
  • Neurobiology 
  • Comprehensive Neuroscience Center 
  • Pathology, research shared with MS2
  • Pharmacology and Toxicology 
  • Physiology and Biophysics 
  • UAB Research Foundation/IIE 
  • Research Administration

Type 1 diabetes: UAB startup gains FDA clearance to test novel oral drug

Type 1 diabetes: UAB startup gains FDA clearance to test novel oral drug
The novel drug TIX100 functions differently from any approved diabetes drug to promote proper islet cell function.

Tiny deletion in heart muscle protein briefly affects embryonic ventricles but has long-term effects on adult atrial fibrillation

Tiny deletion in heart muscle protein briefly affects embryonic ventricles but has long-term effects on adult atrial fibrillation
These findings in zebrafish and human heart muscle cells have clinical implications for patients with atrial fibrillation.

Landmark drug trial shows promising results for Pitt-Hopkins syndrome

Landmark drug trial shows promising results for Pitt-Hopkins syndrome
This devastating neurodevelopmental disorder has no currently approved treatments.

Deep machine-learning speeds assessment of fruit fly heart aging and disease, a model for human disease

Deep machine-learning speeds assessment of fruit fly heart aging and disease, a model for human disease
Use of high-speed video microscopy and artificial intelligence provides calculated statistics like diastolic and systolic diameters, fractional shortening, and ejection fraction.

$18.5 million U19 grant will study B and T memory cells in transplanted lungs, uteruses and kidneys

$18.5 million U19 grant will study B and T memory cells in transplanted lungs, uteruses and kidneys
Indirect benefits could include how to lessen rejection of transplanted organs and damage to the transplanted tissue.

Encouraging Phase 1 data for glioblastoma treatment reported by UAB researchers at ASCO

Encouraging Phase 1 data for glioblastoma treatment reported by UAB researchers at ASCO
Ninety-two percent of evaluable patients treated with INB-200 exceeded a median progression-free survival of seven months. Glioblastoma multiforme is the most aggressive type of cancer originating in the brain.

Second Phase 3 clinical trial again shows dupilumab lessens disease in COPD patients with type 2 inflammation

Second Phase 3 clinical trial again shows dupilumab lessens disease in COPD patients with type 2 inflammation
Chronic obstructive pulmonary disease patients with type 2 inflammation saw rapid and sustained improvements after treatment with the monoclonal antibody dupilumab.

Key role found for gut epithelial cells and their expression of MHCII in the defense against deadly diarrheal infections

Key role found for gut epithelial cells and their expression of MHCII in the defense against deadly diarrheal infections
A newly identified subset of intestinal epithelial cells act as both the major target and a key responder in a mouse model of gut infection by the bacteria Citrobacter rodentium.

Postpartum depression after adolescent stress shows a dysregulated HPA axis: a cross-species translational study

Postpartum depression after adolescent stress shows a dysregulated HPA axis: a cross-species translational study
This serious mental health problem resists treatment, but a mouse model shows a potential new treatment.

Morphine tolerance results from Tiam1-mediated maladaptive plasticity in spinal neurons

Morphine tolerance results from Tiam1-mediated maladaptive plasticity in spinal neurons
Understanding the mechanisms underlying tolerance and hyperalgesia is essential to enhance morphine’s utility in chronic pain management.
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