Jeff Hansen

Jeff Hansen

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Research Editor

jeffhans@uab.edu • (205) 209-2355

Communicates UAB research discoveries and initiatives from across the university for a variety of audiences.

Specific beats include: biochemistry; cell, developmental and integrated biology; microbiology; molecular genetics; neurobiology; pathology; pharmacology and tocixology; Alabama Drug Discovery Alliance; Bill L. Harbert Institute for Innovation and Entrepreneurship.

COVID-19: Do not forget the host in treating this disease

COVID-19: Do not forget the host in treating this disease

An immune reaction to COVID-19 infection called cytokine storm syndrome can be fatal to COVID-19 patients.

Hydrogen sulfide heightens disease in tuberculosis, suggesting a new therapeutic target

Hydrogen sulfide heightens disease in tuberculosis, suggesting a new therapeutic target

The tuberculosis bacteria induce increased hydrogen sulfide production by human macrophages, which increases pathogenesis.

Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells

Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells
Manipulating cellular metabolism may provide a promising therapeutic intervention in autoimmune diseases.

Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization

Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization
This suggests the possibility of cross-talk that heightens pathogenesis in Type 1 diabetes.

Chaplin elected as a distinguished fellow of the American Association of Immunologists

Chaplin elected as a distinguished fellow of the American Association of Immunologists

Chaplin has been chosen as a distinguished fellow by the American Association of Immunologists for his contributions to the field of immunology.

New pathogenic mechanism for influenza NS1 protein found

New pathogenic mechanism for influenza NS1 protein found
Influenza NS1 can bind with the cell’s RIG-I protein, blocking the innate immune response

Link between chronic kidney disease and heart failure is identified in patients

Link between chronic kidney disease and heart failure is identified in patients
Coronary microvascular dysfunction is a precursor to later heart disease, heart failure and possible death.

Unrecognized genetic variation in research mouse models can affect immune cells

Unrecognized genetic variation in research mouse models can affect immune cells
Unsuspected genetic variation among strains of mice can surreptitiously confound data results.

Human fetal lungs harbor a microbiome signature

Human fetal lungs harbor a microbiome signature
This microbiome signature suggests that bacteria, or bacterial products, colonize the lungs far before birth.

Pathogenic Alzheimer’s disease cascade is activated by faulty norepinephrine signaling

Pathogenic Alzheimer’s disease cascade is activated by faulty norepinephrine signaling

Study points to a potential immediate treatment for this devastating disease.

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