Keshav K. Singh, Ph.D., joins the University of Alabama at Birmingham Comprehensive Cancer Center as senior scientist in the Cancer Cell Biology Program, director of the Cancer Genetics Program and the Joy and Bill Harbert Endowed Chair in Cancer Genetics. Singh also is a professor in the departments of Genetics, Pathology and Environmental Health.
Singh’s basic research examines the underlying mechanisms of mitochondria-to-nucleus retrograde signaling, “intergenomic” cross talk and genomic instability. He also is engaged in developing agents and methods that can detect and reverse mitochondrial defects in cells and identify potential "mitomutagens" that may contribute to human pathologies.
Singh also is passionate about promoting research and awareness regarding mysterious mitochondrial diseases arising due to defects in the “power house of the cell.” He is the founder of the Mitochondria Research and Medicine Society in the United States and India, and the founding editor-in-chief of the journal, Mitochondrion. He is an expert grant reviewer and the author of more than 75 research publications and three books, including Mitochondrial DNA Mutations in Aging, Disease and Cancer.
Singh earned his doctorate from University of Wollongong in New South Wales, Australia, and trained as a post-doctoral fellow at Harvard University. He was an assistant professor of oncology at the Sidney Kimmel Cancer Center at Johns Hopkins School of Medicine. Most recently he was at the Roswell Park Cancer Institute where he was a distinguished professor of oncology.