Pilot Projects
Pilot grants funded in 2008:
| Pilot study : | Polyphenols from botanicalson the activity of the Sir2 family of evolutionarily conserved NAD+ dependent deacetylases (Ann Kirchmaier, Purdue) |
| Pilot study : | Analysis of the actions of grape seed extract on neurogenesis in the yound adult rodent brain (Linda Wadiche, UAB) |
Pilot grants funded in 2007:
| Pilot study 1: | The pharmacokinetics and bioavailability of herbal remedies used by rural African-Americans. (Glenda L. Smith, UAB) |
| Pilot study 2: | Isoflavone dependent modulation of the vascular glycocalyx during inflammation. (Rakesh P. Patel, UAB) |
| Pilot study 3: | Effects of mannan on body weight and body composition: a precursor to a longevity study. (David B. Allison, UAB) |
| Pilot study 4: | Chemoprevention of colon carcinogenesis by dietary and medicinal mushrooms (David Sliva/Jiri Adamec, Purdue) |
Pilot grants funded in 2006:
| Pilot study 1: | Gamma Tocopherol as a novel chemoprevention agent in azoxymethane-induced colon cancer model (Qing Jiang, Purdue) |
| Pilot study 2: | Green Tea Formulations for Amelioration of Type 2 Diabetes in the Zucker Diabetic Rat Model with NMR Evaluation of Disease Progress (Elsa M. Janle, Purdue) |
| Pilot study 3: | Efficacy of Grape Seed Extract in Protection Against Vascular Calcification in a Model of Uremia (K. Wilund, Purdue) |
Pilot grants funded in 2005:
| Pilot study 1: | Digestive fate of tea catechins: impact of tea fromulation on catechin
digestive recovery and human intestinal cell uptake (Mario
Ferruzzi, Purdue) |
| Pilot study 2: | Neuroprotective effect of blueberry extract on Parkinson Disease
(Chris Rochet, Purdue) |
Pilot grants funded in 2004:
| Pilot study 1: | Beneficial
Effects of Soy Isoflavonoids on Prevention of Age-related Ocular Damage
in Monkey (Chao-Chen
Wang, UAB) |
| Pilot study 2: | Interactions between green tea polyphenols and intestinal
xenobiotic transporters (David Forster, IUPUI) |
| Pilot study 3: | Chemo-preventive Effects of Cranberry Juice Concentrate on Urinary Bladder carcinogenesis (Clinton Grubbs, UAB) |
Pilot grants funded in 2003:
| Pilot study 1: | Effect of green tea extract of alcohol-induced mitochondrial
dysfunction: a proteomics approach (Shannon M. Bailey, UAB) |
| Pilot study 2: | Genistein-mediated prostate cancer prevention through enhanced vitamin D signaling (Jim Fleet, Purdue) |
| Pilot study 3: | Soy isoflavones in fat cell gene regulation (Young-Cheul Kim, Purdue) |
| Pilot study 4: | Evaluation of telomerase mechanisms in human breast cancer cells after treatment with the polyphenol EGCG (Trygve Tollefsbol, UAB) |
Pilot grants funded in 2002:
| Pilot study 1: | Pinitol Supplementation in humans: Effects on blood and urine inositol concentrations and whole body and muscle glucose metabolism (Wayne Campbell, Purdue ). |
| Pilot study 2: | Oxidation of Kava by Human Cytochrome P450 2D6 Causes Hepatotoxicity
(Luke Lightning, Purdue ). |
| Pilot study 3: | Bioavailability and molecular targets identification of Isoflavones from Kudzu dietary supplements (Jeevan Prasain, UAB ). |
| Pilot study 4: | Do Phytochemicals used to promote Prostate Health have beneficial or detrimental effects on lethal cancer progression? (David Walters, Purdue ) |
Pilot grants funded in 2001:
| Pilot study 1: | Grape seed extract efficacy in a model of hypertension (J. Michael Wyss, UAB) |
| Pilot study 2: | Modulation of monocyte-endothelial cell interactions by polyphenols (Rakesh Patel, UAB) |
| Pilot study 3: | Effect of green tea on glucose tolerance in rats and prevention of diabetes in Zucker diabetic rats: (Elsa Janle, Purdue) |