Explore UAB

 

Link JM, Larson JE, Schroeder HW Jr. 2005. Despite extensive similarity in germline DH and JH sequence, the adult Rhesus macaque CDR-H3 repertoire differs from human. Mol Immunol 42:943-955. PMID: 15829286


Ivanov II, Schelonka RL, Zhuang Y, Gartland GL, Zemlin M, Schroeder HW Jr.  2005.  Development of the expressed immunoglobulin CDR-H3 repertoire is marked by focusing of constraints in length, amino acid utilization, and charge that are first established in early B cell progenitors.  J Immunol 174:7773-7780.  PMID: 15944280


Schelonka RL, Ivanov II, Jung D, Ippolito GC, Nitschke L, Zhuang Y, Gartland GL, Pelkonen J, Alt F, Rajewsky K, Schroeder HW Jr.  2005.  A single DH gene segment is sufficient for B cell development and immune function.  J Immunol 175:6624-6632.  PMID: 16272317


Hsu H-C, Scot DK, Zhang P, Zhou J, Yang PA, Wu Q, Schroeder HW Jr, Gerald LB, Ravussin E, Jazwinski MS, Mountz JD.  2006. CD8 T-cell immune phenotype of successful aging.  Mech Aging Develop 127:231-239.  PMID: 16313945


Johnston DT, Mehaffey G, Thomas J, Young KR Jr, Wiener H, Li J, Li J, Go RCP, Schroeder HW Jr.  2006.  Increased frequency of HLA *B44 in recurrent sinopulmonary infections (RESPI). Clin Immunol 119:346-350.  PMID: 16542878


Ippolito, GC, Schelonka RL, Zemlin M, Ivanov I, Kobayashi R, Zemlin C, Gartland L, Nitschke L, Pelkonnen J, Fujihashi K, Rajewsky K, Schroeder HW Jr. 2006.  Forced use of an immunoglobulin DH encoding positively charged amino acids impairs B cell development and function.  J Exp Med 203:1567-157.  PMID: 16754718


Johnston DT, Schroeder HW Jr.  2007.  B-cell numbers in the blood of patients with non-HLA*B8 or non-HLA*B44 common variable immunodeficiency. Ann Allergy Asthma Immunol. 98(2):163-167.  PMID: 17304884


Schelonka RL, Tanner J, Zhuang Y, Gartland GL, Zemlin M, Schroeder HW Jr. 2007. Categorical selection of the antibody repertoire in splenic B cells. Eur J Immunol 37(4):1010-1021. PMID: 17345580


Li J, Cowden LG, King JD, Briles DA, Schroeder HW Jr, Stevens AB, Perry RT, Chen Z, Simmons MS, Wiender HW, Tiwari H, Harrell LE, Go RCP.  2007. Effects of chronic stress and interleukin-10 polymorphisms on antibody response to tetanus vaccine in family caregivers of patients with Alzheimer’s Disease.  Psychosom Med 69:551-559.  PMID: 17634568


Nguyen HH, Zemlin M, Vu HL, Ivanov II, Andrasi J, Zemlin C, Schelonka RL, Schroeder HW Jr, Mestecky J.  2007. Heterosubtypic immunity to influenza A virus infection requires a properly diversified antibody repertoire.  J Virol 81:9331-9338.  PMID: 17567700


Schelonka RL, Zemlin M, Kobayashi R, Ippolito GC, Zhuang Y, Gartland GL, Fujihashi K, Rajewsky K, Schroeder HW Jr. 2008.  Preferential use of DH reading frame 2 alters B cell development and antigen-specific antibody production.  J Immunol 181(12): 8409-8415. PMID: 19050258.


Zemlin M, Schelonka RL, Ippolito GC, Zemlin C, Zhuang Y, Gartland GL, Nitschke L, Pelkonen J, Rajewsky K, Schroeder HW Jr. 2008.  Regulation of repertoire development through genetic control of DH reading frame preference. J Immunol 181(12): 8416-8424.  PMID: 19072309.


Kerzel S, Wagner J, Rogosch T, Yildirim AO, Sikula L, Fehrenbach H, Garn H, Maier RF, Schroeder HW Jr, Zemlin M. 2009. Composition of the immunoglobulin classic antigen-binding site regulates allergic airway inflammation in a murine model of experimental asthma. Clin Exp Allergy. 39(4):455-7. PMID: 19220320


Waldrep ML, Zhuang Y, Schroeder HW Jr. 2009. Analysis of TACI mutations in CVID & RESPI patients who have inherited HLA B*44 or HLA*B8. BMC Med Genet. 10:100. PMID: 19775471


Vale AM, Hayashi E, Granato A, Schroeder HW Jr, Bellio M, Nobrega A. 2010. Genetic control of the B cell response to LPS: opposing effects in peritoneal versus splenic B cell populations. Immunogenetics. 62(1):41-8. PMID: 19937016


Wang C, Sanders CM, Yang Q, Schroeder HW Jr, Wang E, Babrzadeh F, Gharizadeh B, Myers RM, Hudson JR Jr, Davis RW, Han J. 2010. High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets. Proc Natl Acad Sci U S A. 107(4):1518-23. PMID: 20080641


Schelonka RL, Szymanska E, Vale AM, Zhuang Y, Gartland GL, Schroeder HW Jr. 2010. DH and JH usage in murine fetal liver mirrors that of human fetal liver. Immunogenetics. 62(10):653-66. PMID: 20714894


Vale AM, Tanner JM, Schelonka RL, Zhuang Y, Zemlin M, Gartland GL, Schroeder HW Jr. 2010. The peritoneal cavity B-2 antibody repertoire appears to reflect many of the same selective pressures that shape the B-1a and B-1b repertoires. J Immunol. 185(10):6085-95. PMID: 20956345 PMCID: PMC3667605


Schelonka RL, Ivanov II, Vale AM, Szymanska E, Zemlin M, Gartland GL, Schroeder HW Jr. 2010. The CDR-H3 repertoire from TdT-deficient adult bone marrow is a close, but not exact, homologue of the CDR-H3 repertoire from perinatal liver. J Immunol. 185(10):6075-84. PMID: 20956348 PMCID: PMC3670101


Schelonka RL, Ivanov II, Vale AM, Dimmitt RA, Khaled M, Schroeder HW Jr. 2011. Absence of N addition facilitates B cell development, but impairs immune responses. Immunogenetics. 63(9):599-609. PMID: 21660592 PMCID: PMC3181008


Mahmoud TI, Schroeder HW Jr, Kearney JF. 2011. Limiting CDR-H3 diversity abrogates the antibody response to the bacterial polysaccharide α 1→3 dextran. J Immunol. 187(2):879-86. PMID: 21677133 PMCID: PMC3210069


Khass M, Buckley K, Kapoor P, Schelonka RL, Watkins LS, Zhuang Y, Schroeder HW Jr. 2013. Recirculating bone marrow B cells in C57BL/6 mice are more tolerant of highly hydrophobic and highly charged CDR-H3s than those in BALB/c mice. Eur J Immunol. 43(3):629-40. PMID: 23225217 PMCID: PMC3653428


Vale AM, Kapoor P, Skibinski GA, Elgavish A, Mahmoud TI, Zemlin C, Zemlin M, Burrows PD, Nobrega A, Kearney JF, Briles DE, Schroeder HW Jr. 2013. The link between antibodies to OxLDL and natural protection against pneumococci depends on D(H) gene conservation. J Exp Med. 210(5):875-90. PMID: 23589567 PMCID: PMC3646500


Mroczek ES, Ippolito GC, Rogosch T, Hoi KH, Hwangpo TA, Brand MG, Zhuang Y, Liu CR, Schneider DA, Zemlin M, Brown EE, Georgiou G, Schroeder HW Jr. 2014. Differences in the composition of the human antibody repertoire by B cell subsets in the blood. Front Immunol. 5:96. PMID: 24678310 PMCID: PMC3958703


Trad A, Tanasa RI, Lange H, Zemlin M, Schroeder HW Jr, Lemke H. 2014. Clonal Progression during the T Cell-Dependent B Cell Antibody Response Depends on the Immunoglobulin DH Gene Segment Repertoire. Front Immunol.5:385. PMID: 25157256 PMCID: PMC4128299


Yuge Wang, Pratibha Kapoor, Robert Parks, Aaron Silva-Sanchez, S. Munir Alam, Laurent Verkoczy, Hua-Xin Liao, Yingxin Zhuang, Peter Burrows, Michael Levinson, Ada Elgavish, Xiangqin Cui, Barton F. Haynes and Harry Schroeder Jr. 2016. HIV-1 gp140 epitope recognition is influenced by immunoglobulin DH gene segment sequence. Immunogenetics. 68(2):145-55. PMID: 26687685 PMCID: PMC4729650


Wang Y, Hwangpo T, Martin MP, Vince N, Qi Y, Reynolds RJ 4th, Absher D, Gao X, Ballinger CA, Burrows PD, Atkinson TP, Brown EE, Elgavish A, Liu C, Carrington M, Schroeder HW. 2016. Killer cell immunoglobulin-like receptors are associated with common variable immune deficiency pathogenesis. J Allergy Clin Immunol. 138(5):1495-1498. PMID: 27665490


Mohamed Khass, Robert L. Schelonka, Cun Ren Liu, Ada Elgavish, Laurence Morel, Peter D. Burrows, Harry W. Schroeder, Jr. 2017. Alterations in B cell development, CDR-H3 repertoire and dsDNA-binding antibody production among C57BL/6 ΔD−iD mice congenic for the lupus susceptibility loci sle1, sle2 or sle3. Autoimmunity 50: 42-51.

 


Recent Invited Reviews and Textbook Chapters


Torres RM, Imboden J, Schroeder HW Jr 2008.  Antigen receptor genes, gene products, and co-receptors.  In: Clinical Immunology: Principles and Practices, 3nd edition, eds. Rich R, Fleisher TA, Shearer WT, Schroeder HW Jr, Frew AJ, Weyand CM.  Elsevier, London.


Berek C, Radbruch A, Schroeder HW Jr.  2008.  B cell development and differentiation.  In: Clinical Immunology: Principles and Practices, 3nd edition, eds. Rich R, Fleisher TA, Shearer WT, Schroeder HW Jr, Frew AJ, Weyand CM.  Elsevier, London.


Schroeder HW Jr
2008.  Primary antibody deficiencies.  In: Clinical Immunology: Principles and Practices, 3nd edition, eds. Rich R, Fleisher TA, Shearer WT, Schroeder HW Jr, Frew AJ, Weyand CM.  Elsevier, London.


Schroeder HW Jr
, Wald D, Greenspan NS.  2008.  Immunoglobulins: Structure and Function.  In:  Fundamental Immunology, edition, eds. .


Cooper MD, Schroeder HW Jr.  2008.  Primary immune deficiency diseases.  In:  Harrison’s Principles of Internal Medicine, 17th edition.


Schroeder HW Jr, Cavacini L. 2010. Structure and function of immunoglobulins. J Allergy Clin Immunol. 125(2 Suppl 2):S41-52. PMID: 20176268


Vale AM, Schroeder HW Jr. 2010. Clinical consequences of defects in B-cell development. J Allergy Clin Immunol. 125(4):778-87. PMID: 20371392


Schroeder HW Jr,
Zemlin M, Khass M, Nguyen HH, Schelonka RL. 2010. Genetic control of DH reading frame and its effect on B-cell development and antigen-specifc antibody production. Crit Rev Immunol. 30(4):327-44. PMID: 20666706


Books


Rich RR, Fleisher TA, Shearer WT, Kotzin B, Schroeder HW Jr. Clinical Immunology: Principles and Practices, 2nd edition, Harcourt International, London.


Rich RR, Fleisher TA, Shearer WT, Schroeder HW Jr, Frew AJ, Weyand CM.  Clinical Immunology: Principles and Practices, 3nd edition, Elsevier, London.