UAB Neurosurgery works to improve clinical care for neurosurgical disorders through clinical trials. Our faculty our currently conducting the following clinical trials. For questions about clinical trials contact the UAB Neurosurgery Office of Clinical Research.
-
Brain Tumor
James M. Markert, M.D., MPH
- A Phase I Trial of IRS-1 HSV C134 Administered Intratumorally in Patients with Recurrent Malignant Glioma; NCT#: 03657576
- Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1); NCT#: 06193174
- Study of Pembrolizumab and M032 (NSC 733972); NCT#: 05084430
- Trial of C134 in Patients With Recurrent GBM (C134-HSV-1); NCT#: 03657576
- Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma (M032-HSV-1); NCT#: 02062827
-
Cognitive and Movement Disorders
J. Nicole Bentley, M.D.
- Investigating Dynamic Interactions in Distributed Cognitive Control Networks; NCT#: 05927974
- Investigating Inhibitory Control Networks in Parkinson's Disease; NCT#: 04735458
- Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders; NCT#: 04061135
Zachary Irwin, Ph.D.
Matthew J. Nelson, Ph.D.
- Neurophysiological Mechanisms of Language Comprehension; NCT#: 05283265
-
Neurovascular
Elizabeth Liptrap, M.D.
- Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH); NCT#: 05020535
- Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial (FASTEST); NCT#: 03496883
- Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL® n-BCA (MEMBRANE); NCT#: 04816591
Jesse Jones, M.D.
- INSPIRE Pipeline™ Shield Post Approval Study; NCT#: 05071963
- Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma (EMBOLISE); NCT#: 04402632
- CERENOVUS Neurothrombectomy Devices Registry (EXCELLENT); NCT#: 03685578
Mark R. Harrigan, M.D.
- Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2); NCT#: 02089217
- Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial – Hemodynamics (CREST H); NCT#: 03121209
- Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2); NCT#: 02089217
- REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study (ICH03); NCT#: 05611918
- Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H) (CREST-H); NCT#: 03121209
- Pediatric
-
Other
Marshall T. Holland, M.D., MS
- Therapeutic Mechanisms of Epidural Spinal Cord Stimulation; NCT#: 05556902
Jesse Jones, M.D.
- Chemo-embolization for Head and Neck Cancer; NCT#: 04595981