Our department faculty have been prolific in their grant funding applications of late, and in many cases, successfully funded for their novel and outstanding research concepts.

The following is a list of awards given since March 2018 to UAB Pathology faculty and instructors. Congratulations to each of the individuals listed here and their research/lab teams for your scientific endeavors.

GRANTS AWARDED in the UAB Department of Pathology, March–July, 2018

John Chatham
Division: Molecular & Cellular Pathology
"Disruption of the Clock O-GlcNAc Axis in Diabetic Cardiomyopathy"
Awarded By: National Heart, Lung, and Blood Institute/NIH/DHHS
TYPE OF AWARD: Revised Award
TOTAL DOLLARS AWARDED: $7,350
AWARDED PROJECT PERIOD: 11/01/2017 - 10/31/2018

Casey T Weaver 
Division: Anatomic Pathology
"Th17 Pathway Plasticity in the Pathogenesis of Inflammatory Bowel Disease"
Awarded by: National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 
TYPE OF AWARD: Non-Competing Continuation/Continuation 
TOTAL DOLLARS AWARDED: $330,750
AWARDED PROJECT PERIOD: 07/01/2018 - 06/30/2019

"Specialization of Innate and Adaptive Immune Cells in Intestinal Barrier Function"
Awarded by: National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $455,611
AWARDED PROJECT PERIOD: 03/01/2018 - 02/28/2019

"Specialization of Innate and Adaptive Immune Cells in Intestinal Barrier Function"
Awarded by: National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $455,611
AWARDED PROJECT PERIOD: 03/01/2018 - 02/28/2019

Xinglong Zheng
Division: Laboratory Medicine
"A Novel Zebrafish Model of Thrombotic Thrombocytopenic Purpura"
Awarded by: American Heart Association
TYPE OF AWARD: Original/New
TOTAL DOLLARS AWARDED: $114,368
AWARDED PROJECT PERIOD: 07/01/2018 - 06/30/2020

"Pathogenesis of Thrombotic Microangiopathy"
Awarded by: National Heart, Lung, and Blood Institute/NIH/DHHS
TYPE OF AWARD: Revised Award
TOTAL DOLLARS AWARDED: $9,108
AWARDED PROJECT PERIOD: 04/01/2018 - 03/31/2019

"Pathogenesis of Thrombotic Microangiopathy"
Awarded by: National Heart, Lung, and Blood Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $446,287
AWARDED PROJECT PERIOD: 04/01/2018 - 03/31/2019

Sooryanarayana Varambally
Division: Molecular & Cellular Pathology
"Investigating the Functional Role and Targeting Purine Metabolic Enzyme PAICS in Prostate Cancer"
Awarded by: Cancer Center Support Grant P30
TYPE OF AWARD: Faculty Development Grant
TOTAL DOLLARS AWARDED: $50,000
AWARDED PROJECT PERIOD: July 2018-July 2019

Majd Zayzafoon
Division: Molecular & Cellular Pathology
"Prostate Cancer and Bone Metastasis: Biology and Targeting"
Cedars - Sinai Medical Center
TYPE OF AWARD: Amendment/Mod
TOTAL DOLLARS AWARDED: $52,409
AWARDED PROJECT PERIOD: 03/01/2018 - 02/28/2019

Xu Feng
Division: Molecular & Cellular Pathology
"Prostate Cancer Bone Metastasis Biology and Targeting"
Awarded by: Cedars - Sinai Medical Center
TYPE OF AWARD: Amendment/Mod
TOTAL DOLLARS AWARDED: $11,174
AWARDED PROJECT PERIOD: 03/01/2018 - 02/28/2019

"Development of Novel Therapeutics for Bone Erosion in Rheumatoid Arthritis"
Awarded by: RHEUMATOLOGY RESEARCH FOUNDATION
TYPE OF AWARD: Original/New
TOTAL DOLLARS AWARDED: $400,000
AWARDED PROJECT PERIOD: 07/01/2018 - 06/30/2020 

Rakesh Pravinchandra Patel
Division: Molecular & Cellular Pathology
"Nitrite Dependent Protection Against Cl2 Gas Toxicity Role of Chlorinated Lipids"
Awarded by: National Institute of Environmental Health Sciences/NIH/DHHS
TYPE OF AWARD: Supplement
TOTAL DOLLARS AWARDED: $148,498
AWARDED PROJECT PERIOD: 07/01/2018 - 06/30/2019

"UAB Predoctoral Training Grant in Translational and Molecular Sciences"
Awarded by: National Institute of General Medical Sciences/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $223,608
AWARDED PROJECT PERIOD: 07/01/2018 - 06/30/2019

Upender Manne
Division: Anatomic Pathology
"Therapeutic value of navitoclax based on the expression status of miR-181b and miR-21 in African American and Caucasian Colon Cancer Patients"
TOTAL DOLLARS AWARDED: $56,000
AWARDED PROJECT PERIOD: 07/01/2018  to 06/30/2019

Scott W Ballinger
Division: Molecular & Cellular Pathology
"Training Program in Cardiovascular Pathophysiology"
Awarded by: National Heart, Lung, and Blood Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $132,146
AWARDED PROJECT PERIOD: 07/01/2018 - 06/30/2019

Elizabeth E. Brown
Division: Molecular & Cellular Pathology
"Molecular Characterization of Myeloma and Related Asymptomatic Precursor States"
Awarded by: National Cancer Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $263,388
AWARDED PROJECT PERIOD: 06/01/2018 - 05/31/2019

Yabing Chen
Division: Molecular & Cellular Pathology
"Regulation of Vascular Smooth Muscle Cell Function in Atherosclerosis"
Awarded by: National Heart, Lung, and Blood Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $532,993
AWARDED PROJECT PERIOD: 06/01/2018 - 05/31/2019

"Molecular Regulation of Vascular Calcification in Atherosclerosis"
Awarded by: National Heart, Lung, and Blood Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $367,500
AWARDED PROJECT PERIOD: 05/01/2018 - 04/30/2019

William E Grizzle
Division: Anatomic Pathology
"Collaborative Human Tissue Network"
Awarded by: National Cancer Institute/NIH/DHHS
TYPE OF AWARD: Revised Award
TOTAL DOLLARS AWARDED: $74,055
AWARDED PROJECT PERIOD: 04/01/2018 - 03/31/2019

"Theranostic Nanoparticles for Detection and Treatment of Pancreatic Cancer"
Awarded by: Wake Forest University
TYPE OF AWARD: Amendment/Mod
TOTAL DOLLARS AWARDED: $21,975
AWARDED PROJECT PERIOD: 07/01/2017 - 06/30/2018

Zdenek Hel
Division: Molecular & Cellular Pathology
"Neutrophil Dysregulation as a Driving Mechanism of Cardiovascular Disease in HIV-1-Infection"
Awarded by: National Heart, Lung, and Blood Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $569,206
AWARDED PROJECT PERIOD: 06/01/2018 - 05/31/2019

Joseph L Messina
Division: Molecular & Cellular Pathology
"IPA - "VA-IPA" Trauma and Hemorrhage-Induced Skeletal Muscle Insulin Resistance"
Awarded by: Veterans Administration
TYPE OF AWARD: Original/New
TOTAL DOLLARS AWARDED: $140,816
AWARDED PROJECT PERIOD: 12/31/2017 - 12/30/2019

Selvarangan Ponnazhagan
Division: Molecular & Cellular Pathology
"Targeted Therapy for Breast Cancer with Osteolytic Bone Damage"
Awarded by: National Cancer Institute/NIH/DHHS
TYPE OF AWARD: Revised Award
TOTAL DOLLARS AWARDED: $33,627
AWARDED PROJECT PERIOD: 03/01/2018 - 02/28/2019

Lalita R Samant
Division: Molecular & Cellular Pathology
"Mechanisms of Resistance to Cancer Therapeutics"
Awarded by: National Cancer Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $305,025
AWARDED PROJECT PERIOD: 06/01/2018 - 05/31/2019

Rajeev S. Samant
Division: Molecular & Cellular Pathology
"Dietary Intervention of Non-Classical Wnt Signaling"
Awarded by; National Cancer Institute/NIH/DHHS
TYPE OF AWARD: Revised Award
TOTAL DOLLARS AWARDED: $33,627
AWARDED PROJECT PERIOD: 04/01/2018 - 03/31/2019

"Dietary Intervention of Non-Classical Wnt Signaling"
Awarded by: National Cancer Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $302,636
AWARDED PROJECT PERIOD: 04/01/2018 - 03/31/2019

Ralph D Sanderson
Division: Molecular & Cellular Pathology
"Heparanase In Tumor Progression, Metastasis and Chemoresistance"
Awarded by: National Cancer Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $354,229
AWARDED PROJECT PERIOD: 06/01/2018 - 05/31/2019

"Heparanase Regulation of Myeloma Metastasis: Mechanism and Therapy"
Awarded by: National Cancer Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $330,750
AWARDED PROJECT PERIOD: 05/01/2018 - 04/30/2019

Victor M Darley-Usmar
Division: Molecular & Cellular Pathology
Awarded by Leidos Biomedical Research, Inc.
Division: Molecular & Cellular Pathology
TYPE OF AWARD: Amendment/Mod
TOTAL DOLLARS AWARDED: $26,862
AWARDED PROJECT PERIOD: 09/30/2017 - 09/22/2018

Wei Chen
Division: Molecular & Cellular Pathology
Characterizing the Mechanism by which Endogenous Negative Regulators of Osteoclasts
"Control Bone Homeostasis under Physiological and Pathological Conditions in Mouse Models"
Awarded by: National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $326,700
AWARDED PROJECT PERIOD: 04/01/2018 - 03/31/2019

Yi-Ping Li
Division: Molecular & Cellular Pathology
"Inhibiting Periodontitis by Targeting Cathepsin K and Attenuating TLR Signaling"
Awarded by: National Institute of Dental and Craniofacial Research/NIH/DHHS
TYPE OF AWARD: Revised Award
TOTAL DOLLARS AWARDED: $48,661
AWARDED PROJECT PERIOD: 12/01/2017 - 11/30/2018 

"Heparanase Regulation of Myeloma Metastasis: Mechanism and Therapy"
Awarded by: National Cancer Institute/NIH/DHHS
TYPE OF AWARD: Non-Competing Continuation/Continuation
TOTAL DOLLARS AWARDED: $330,750
AWARDED PROJECT PERIOD: 05/01/2018 - 04/30/2019

Z. Long Zheng
Division: Lab Medicine
"Patholgenesis of Thrombotic Microangiopathy"
Awarded by: National Heart, Lung, and Blood Institute (NHLBI)
TYPE OF AWARD: New R01