Contact:
Held On: February 15, 2008
Location: Learning Resources Center, Room 102
University of Alabama at Birmingham Campus
Primary Sponsors:
- UAB'S Clinical Nutrition Research Center (CNRC)
- Howell and Elizabeth Heflin Center for Human Genetics
Co-Sponsors:
- Arthritis and Musculoskeletal Diseases Center
- Center for AIDS Research
- Center for Free Radical Biology
- Center for Metabolic Bone Disease
- Center for Women's Reproductive Health
- Civitan International Research Center
- Comprehensive Cancer Center
Organizers:
Jose R. Fernandez, Ph.D.
Associate Professor, Department of Nutrition Sciences
University of Alabama at Birmingham
David B. Allison, Ph.D.
Director, Clinical Nutrition Research Center
Professor, Departments of Biostatistics and Nutrition Sciences
University of Alabama at Birmingham
Donna K. Arnett, Ph.D.
Professor and Chair, Department of Epidemiology
University of Alabama at Birmingham
Jan P. Dumanski, Ph.D.
Professor, Department of Genetics
Director, Howell and Elizabeth Heflin Center for Human Genetics
Senior Scientist, Comprehensive Cancer Center
University of Alabama at Birmingham
Overview
Advances in molecular biology continue to move the field of genetics to new horizons. No longer are we only concerned with SNP or microsatellite variation in nuclear DNA. A range of promising new technologies allows scanning of the entire human genome for new types of variations with accuracy and efficiency. The extent to which new technologies can be used to identify the molecular basis of trait variation and disease risk is a topic of interest among UAB scientists and researchers who wish to work at the frontier of genetic science. This program is meant to introduce some of these new technologies. Morning sessions will consist of scientific overviews by outstanding internationally recognized speakers. These presentations will emphasize what can be done. Afternoon sessions will consist of presentations that emphasize at a very practical level how to get the job done.
Distinguished Speakers
Charles Lee, Ph.D.
Director of Cytogenetics, Harvard Cancer Center
Assistant Professor, Harvard Medical School
Carmen Sapienza, Ph.D.
Professor, Department of Pathology
Associate Director, Fels Institute for Cancer Research and Molecular Biology
Temple University
Joseph Costello, Ph.D.
Associate Professor, Department of Neurological Surgery
University of California San Francisco
Carlo M. Croce, M.D.
Director, Institute of Genetics
Chair Molecular Virology, Immunology & Medical Genetics
Ohio State University
Schedule
| Time | Topic | Presenter | Resources |
|---|---|---|---|
| 8:00-8:20 AM | Registration/Breakfast | ||
| 8:20-8:30 AM | Welcome Remarks | David B Allison, Donna Arnett, & Jose Fernandez | Watch Video |
| 8:30-9:15 AM | Structural Genomic Variation and Human Health | Charles Lee, Ph.D. | Watch Video |
| 9:15-10:00 AM | Causes and Consequences of Epigenetic Variation in the Human Population | Carmen Sapienza, Ph.D. | Watch Video |
| 10:00-10:30 AM | BREAK | ||
| 10:30-11:30 AM | Techniques for DNA Methylation Profiling and Their Application to Comparative Epigenomics | Joseph Costello, Ph.D. | Watch Video |
| 11:30-12:00 PM | Role of MicroRNAs in Human Cancer | Carlo M Croce, MD | Watch Video |
| 12:00-1:30 PM | LUNCH | ||
| 1:30-2:15 PM | Somatic Mosaicism for CNVs; Analysis of Monozygotic Twins and Differentiated Human Tissues, and Practical Aspects of Assessing Copy Number Variation | Jan Dumanski, Ph.D. | Watch Video |
| 2:15-3:00 PM | Practical Aspects of Studying MicroRNA | Carlo M Croce, M.D. | |
| 3:00-3:30 PM | Practical Aspects of Assessing Genomewide Methylation/Epigenetics | Carmen Sapienza, Ph.D. | |