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Carbohydrates are directly linked to the development of Type 2 diabetes, but a higher-carb diet is underused in research models.
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A study from the University of Alabama at Birmingham is looking into a drug-free approach to treat type 2 diabetes. The research focuses on using diet changes to target the fat around organs like the pancreas and liver.
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W. Timothy Garvey, M.D., was named University Professor in the School of Health Professions Department of Nutrition Sciences. Garvey joined UAB in 2003 as chair of the Department of Nutrition Sciences, where he served until 2018.
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A novel therapy developed at the University of Alabama at Birmingham ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet. The therapy acts through sustained release of nitric oxide, a gaseous signaling chemical whose most important function in the body is relaxing the inner muscles of blood vessels.
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According to the Centers for Disease Control and Prevention, more than 37 million Americans have diabetes, and approximately 90-95 percent of them have Type 2 diabetes. Individuals with Type 2 diabetes are at an increased risk of poor cardiovascular outcomes, leading to an estimated $37.3 billion a year in heart disease-associated care.
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Maintaining a healthy diet is important for your body’s overall health, reducing risk from many chronic noncommunicable diseases, such as diabetes, heart disease and cancer.
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In a recent study published in Circulation: Genomic and Precision Medicine, University of Alabama at Birmingham researchers found that, while many African Americans, especially those with a higher African ancestry proportion, have a favorable lipid profile, they are at a higher risk of developing diabetes than those of white/European ancestry. A favorable lipid profile indicates there are fewer components of body fat that can lead to cardiovascular and metabolic disease. Researchers believe this may be driven by genetic factors associated with geographic ancestry.
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Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications. Patients taking the oral blood pressure medication not only required less daily insulin two years after first diagnosis of the disease, but also showed evidence of surprising immunomodulatory benefits.
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The undue burden of obesity, diabetes and hypertension in the Deep South is a focus for the 2021 Marchase Award winner, Andrea Cherrington, M.D. The award celebrates and encourages interdisciplinary work at the University of Alabama at Birmingham.
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The University of Alabama at Birmingham, in partnership with other leading academic centers in Alabama, Mississippi and Louisiana, will establish the Deep South Center to Reduce Disparities in Chronic Diseases with a grant from the National Institutes of Health.