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Publications Resulting from OKRA NRC Support

  • 2024
    1. Qiao Xuanyuan, Haojia Wu, Benjamin D Humphreys. Emerging high resolution spatial transcriptomic technologies in kidney research. Nephrol Dial Transplant. 2024 Jun 4:gfae125. doi: 10.1093/ndt/gfae125. PMID: 38834536.
    2. Haojia Wu, Eryn E Dixon, Qiao Xuanyuan, Juanru Guo, Yasuhiro Yoshimura, Chitnis Debashish, Anezka Niesnerova, Hao Xu, Morgane Rouault, Benjamin D Humphreys. High resolution spatial profiling of kidney injury and repair using RNA hybridization-based in situ sequencing. Nat Commun . 2024 Feb 15;15(1):1396.. doi: 10.1038/s41467-024-45752-8. PMID: 38360882; PMCID: PMC10869771
    3. Bondi CD, Hartman HL, Tan RJ. NRF2 in kidney physiology and disease. Physiol Rep. 2024 Mar;12(5):e15961. doi: 10.14814/phy2.15961. PMID: 38418382; PMCID: PMC10901725.
    4. Boyd-Shiwarski CR, Shiwarski DJ, Subramanya AR. A New Phase for WNK Kinase Signaling Complexes as Biomolecular Condensates. Physiology. 2024 April 16. PubMed PMID: 38624245; doi: 10.1152/physiol.00013.2024.
    5. Carrisoza-Gaytan R, Mutchler SM, Carattino F, Soong J, Dalghi MG, Wu P, Wang WH, Apodaca G, Satlin LM, Kleyman TR. PIEZO1 is a distal nephron mechanosensor and is required for flow-induced K+ secretion. J Clin Invest. 2024 Mar 1;134(5):e174806. PMID: 38426496. PMCID: PMC10904061
    6. Ertuglu LA, Mutchler AP, Laffer CL, Saleem M, Sahinoz M, Sheng Q, Wanjalla CN, Pakala S, Gutierrez OM, Kleyman TR, Ikizler TA, Kirabo A. Eicosanoid-regulated Myeloid ENaC and isolevuglandin formation in human salt-sensitive hypertension. Hypertension. 2024 March;81(3):516-529. PubMed PMID: 37675576; PubMed Central PMCID: PMC10918035; DOI: 10.1161/HYPERTENSIONAHA.123.21285.
    7. Farrell CE, Liu X, Yagan NO, Suda AC, Cerqueira DM, Bodnar AJ, Kashlan OB, Subramanya AR, Ho J, Butterworth MB. MicroRNA-19 is regulated by aldosterone in a sex-specific manner to alter kidney sodium transport.Am J Physiol Cell Physiol. 2024 Jan 1;326(1):C282-C293. doi: 10.1152/ajpcell.00385.2023. Epub 2023 Dec 4. PMID: 38047299
    8. Kashlan OB, Wang X, S. Sheng S, Kleyman TR. Epithelial Na+ channels function as extracellular sensors. Compr Physiol. 14:5407-5447, 2024. PMCID in process.
    9. Lackner EM, Cowan IA, Long KR, Weisz OA, Shipman KE. Fluid Shear Stress-Induced Changes in Megalin Trafficking Enhance Endocytic Capacity in Proximal Tubule Cells. bioRxiv [Preprint]. 2024 Mar 19:2024.02.22.581213. doi: 10.1101/2024.02.22.581213. PMID: 38562767
    10. Mutchler SM, Hasan M, Murphy CP, Baty CJ, Boyd-Shiwarski C, Kirabo A, Kleyman TR. Dietary sodium alters aldosterone’s effect on renal sodium transporter expression and distal convoluted tubule remodeling. J Physiol. 602:967-987, 2024. PMID: 38294810. PMCID: PMC10939779
    11. Mutchler, SM, Whelan SC, Marciszyn A, Chen J, Kleyman TR, and Shi S. Role of paraoxonase 3 in regulating ENaC-mediated Na+ transport in the distal nephron. J Physiol. 602:737-757, 2024. PMID: 38345534. PMCID: PMC10940207
    12. Porter A, Vorndran HE, Marciszyn A, Mutchler SM, Subramanya AR, Kleyman TR, Hendershot LM, Brodsky JL, Buck TM. Excess dietary sodium partially restores salt and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron. bioRxiv [Preprint]. 2024 Jan 14:2024.01.13.575426. PMID: 38260467. PMCID: PMC10802592.
    13. Ray EC, Nickerson A, Sheng S, Carrisoza-Gaytan R, Lam T, Marciszyn A, Zhang L, Jordahl A, Bi C, Winfrey A, Kou Z, Gingras S, Kirabo S, Satlin LM, Kleyman TR. Influence of proteolytic cleavage of ENaC’s g subunit upon Na+ and K+ handling. Am J Physiol. 2024 April 18. PubMed PMID: 38634134; DOI: 10.1152/ajprenal.00027.2024.
    14. Rein J, Mackie K, Kleyman TR, Satlin LM. Cannabinoid receptor activation causes a water diuresis by inducing an acute central diabetes insipidus in mice. Am J Physiol. 2024 April 18. PubMed PMID: 38634131; DOI: 10.1152/ajprenal.00320.2022.
    15. Wolf-Johnston A, Ikeda Y, Zabbarova I, Kanai AJ, Bastacky S, Moldwin R, Stern JN, Jackson EK, Birder LA. Purine nucleoside phosphorylase inhibition is an effective approach for the treatment of chemical hemorrhagic cystitis. JCI Insight. 2024 Mar 8;9(5):e176103. doi: 10.1172/jci.insight.176103. PMID: 38271096; PMCID: PMC10972598.
  • 2023
    1. Apodaca G. Defining the molecular fingerprint of bladder and kidney fibroblasts. Am J Physiol Renal Physiol. 2023 Dec 1;325(6):F826-F856. doi: 10.1152/ajprenal.00284.2023. Epub 2023 Oct 12. PMID: 37823192; PMCID: PMC10886799.
    2. Birder, L.A., Wolf-Johnston, A.S., Zabbarova, I., Ikeda, Y., Robertson, A.M., Cardozo, R., Azari, F., Kanai, A.J., Kuchel, G.A., and Jackson, E.K.: Hypoxanthine induces signs of bladder aging with voiding dysfunction and lower urinary tract remodeling. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2023 Jul 18:glad171. doi: 10.1093/gerona/glad171. Online ahead of print PMID: 37463319
    3. Cervino AS, Collodel MG, Lopez IA, Hochbaum D, Hukriede NA, Cirio MC. Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation. Sci Rep. 2023 Oct 4;13(1):16671. doi: 10.1038/s41598-023-43662-1.
    4. Cosgrove HA, Gingras S, Kim M, Bastacky S, Tilstra JS, Shlomchik MJ. B cell-intrinsic TLR7 expression drives severe lupus in TLR9-deficient mice. JCI insight. 2023 August 22;8(16). PubMed PMID: 37606042; PubMed Central PMCID: PMC10543715; DOI: 10.1172/jci.insight.172219.
    5. DeGiosio RA, Needham PG, Andrews OA, Tristan H, Grubisha MJ, Brodsky JL, Camacho C, Sweet RA. Differential regulation of MAP2 by phosphorylation events in proline-rich versus C-terminal domains. FASEB J. 2023 Oct;37(10):e23194. doi: 10.1096/fj.202300486R. PMID: 37702880
    6. Gui Y, Palanza Z, Gupta P, Li H, Pan Y, Wang Y, Hargis G, Kreutzer DL, Wang Y, Bastacky SI, Liu Y, Liu S, Zhou D. Calponin 2 regulates ketogenesis to mitigate acute kidney injury. JCI Insight. 2023 Nov 8;8(21):e170521. doi: 10.1172/jci.insight.170521. PMID: 37751293; PMCID: PMC10721266.
    7. Jackson, E.K., Tofovic, S.P., Chen, Y., and Birder, L.A.: 8-Aminopurines in the cardiovascular and renal systems and beyond. Hypertension 280: 2265-2279, 2023. PMC10592300, PMID: 37503660
    8. Long KR, Rbaibi Y, Kashlan OB, Weisz OA. Receptor-associated protein impairs ligand binding to megalin and megalin-dependent endocytic flux in proximal tubule cells. Am J Physiol. Renal Physiol. 2023 October 1;325(4):F457-F464. PubMed PMID: 37534387; DOI: 10.1152/ajprenal.00165.2023.
    9. Montalbetti N, Dalghi MG, Parakala-Jain T, Clayton D, Apodaca G, Carattino MD. Antinociceptive effect of the calcitonin gene-related peptide receptor antagonist BIBN4096BS in mice with bacterial cystitis. Am J Physiol Renal Physiol. 2023 Dec 1;325(6):F779-F791. doi: 10.1152/ajprenal.00217.2023. Epub 2023 Oct 12. PMID: 37823199; PMCID: PMC10878727.
    10. Nguyen, N.H., S. Sarangi, E.M. McChesney, S. Sheng, J.D. Durrant, A.W. Porter, T.R. Kleyman, Z.W. Pitluk and J.L. Brodsky. Genome mining yields new disease-associated ROMK variants with distinct defects. PLOS Genetics. 19:e1011051, 2023. PMID: 37956218. PMCID: PMC10695394.
    11. Nickerson, AJ, Mutchler SM, Sheng S, Cox NA, Ray EC, Kashlan OB, Carattino MD, Marciszyn AL, Winfrey A, Gingras S, Kirabo A, Hughey RP, Kleyman TR. Mice lacking gENaC palmitoylation sites maintain benzamil-sensitive Na+ transport despite reduced ENaC activity. JCI Insight. 8:e172051, 2023. PMID: 37707951. PMCID: PMC10721255.
    12. Pitzer Mutchler A, Huynh L, Patel R, Lam T, Bain D, Jamison S, Kirabo A, Ray EC. The role of dietary magnesium deficiency in inflammatory hypertension. Frontiers in physiology. 2023;14:1167904. PubMed PMID: 37293263; PubMed Central PMCID: PMC10244581; DOI: 10.3389/fphys.2023.1167904.
    13. Tabibzadeh N, Satlin LM, Jain S, Morizane R. Navigating the kidney organoid: insights into assessment and enhancement of nephron function. Am J Physiol. Renal Physiol. 2023 December 1;325(6):F695-F706. PubMed PMID: 37767571; PubMed Central PMCID: PMC10878724; DOI: 10.1152/ajprenal.00166.2023.
    14. Tilstra JS, Kim M, Gordon RA, Leibler C, Cosgrove HA, Bastacky S, Nickerson KM, Shlomchik MJ. B cell-intrinsic Myd88 regulates disease progression in murine lupus. J Exp Med. 2023 Dec 4;220(12):e20230263. doi: 10.1084/jem.20230263. Epub 2023 Oct 3. PMID: 37787782; PMCID: PMC10541815.
    15. Tyagi S, Resnick NM, Clarkson BD, Zhang G, Krafty RT, Perera S, Subramanya AR, Buysse DJ. Impact of sleep on chronobiology of micturition among healthy older adults. Am J Physiol Renal Physiol. 2023 Oct 1;325(4):F407-F417. doi: 10.1152/ajprenal.00025.2023. Epub 2023 Aug 10. PMID: 37560770
    16. Veloso Pereira BM, Zeng Y, Maggiore JM, Eng DG, Kaverina N, McKinzie SR, Chang A, O’Connor C, Loretz CJ, Hukriede NA, Pippin JW, Wessely O, Shankland SJ. Podocyte Injury at Young Age Causes Premature Senescence and Worsens Glomerular Aging. Am J Physiol Renal Physiol Oct 19. doi: 10.1152/ajprenal.00261.2023.
    17. Wang XP, Mutchler SM, Carrisoza-Gáytan R, Al-Bataineh M, Baty CJ, Vandevender A, Srinivasan P, Tan RJ, Jurczak MJ, Satlin LM, Kashlan OB. Mineralocorticoid receptor-independent activation of ENaC in a mouse model of cholestatic liver disease. bioRxiv. 2023 Sep 22:2023.09.19.558474. doi: 10.1101/2023.09.19.558474. Preprint. PMID: 37790468. PMCID: PMC10542149.
    18. Border S, Lucarelli N, Eadon MT, El-Achkar TM, Jain S, Sarder P. Computational Pathology Fusing Spatial Technologies. Clin J Am Soc Nephrol. 2023 Mar 13. eng. Epub 2023/03/14. doi:10.2215/cjn.0000000000000146. Cited in: Pubmed; PMID 36913267.
    19. Bryniarski MA, Sandoval RM, Ruszaj DM, Fraser-McArthur J, Yee BM, Yacoub R, Chaves LD, Campos-Bilderback SB, Molitoris BA, Morris ME. Defining the Intravital Renal Disposition of Fluorescence-Quenched Exenatide. Mol Pharm. 2023 Feb 6;20(2):987-996. eng. Epub 2023/01/11. doi:10.1021/acs.molpharmaceut.2c00671. Cited in: Pubmed; PMID 36626167.
    20. Wagner MC, Sandoval RM, Yadav SPS, Campos SB, Rhodes GJ, Phillips CL, Molitoris BA. Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity. Kidney360. 2023 Feb 27. eng. Epub 2023/02/28. doi:10.34067/kid.0000000000000094. Cited in: Pubmed; PMID 36848531.
    21. Winfree S, McNutt AT, Khochare S, Borgard TJ, Barwinska D, Sabo AR, Ferkowicz MJ, Williams JC, Jr., Lingeman JE, Gulbronson CJ, Kelly KJ, Sutton TA, Dagher PC, Eadon MT, Dunn KW, El-Achkar TM. Integrated Cytometry With Machine Learning Applied to High-Content Imaging of Human Kidney Tissue for In Situ Cell Classification and Neighborhood Analysis. Lab Invest. 2023 Feb 4;103(6):100104. eng. Epub 2023/03/04. doi:10.1016/j.labinv.2023.100104. Cited in: Pubmed; PMID 36867975.

 

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