Research - News
This finding suggests utility of treatments before fecal microbial transplants to reduce recipient microbial communities. This would help donor microbial strains dominate in the recipient.
The gift will advance the use of induced pluripotent stem cells as a potential therapy for Alzheimer’s disease.
Experiments reveal that a catalytic subunit of CK2, called CK2α, is an important regulator of mouse CD8+ T cell activation, metabolic reprogramming and differentiation, both in vitro and in a mouse-infection model by the intracellular pathogen Listeria monocytogenes.
At their annual Innovation Awards, UAB’s Bill L. Harbert Institute for Innovation and Entrepreneurship celebrated innovators from all corners of campus for their accomplishments, inventions and ingenuity.
Gould’s helmet research added variables such as fall height and the type of surface struck.
The funding will be used to purchase cutting-edge equipment to assist with high-containment research productivity and pandemic preparedness at UAB.
Insights gained from this project can lead to a new understanding of the mechanisms by which human deep-brain activity gives rise to cognitive-emotional behaviors, such as social thought processes, impulsivity and affect.
Direct reprogramming is a potential therapy for heart attack patients. In vitro, TBX20 improved contractility and mitochondrial function of reprogrammed heart muscle cells.
Diseases linked to atherosclerosis are the leading cause of death in the United States.
The new, one-of-a-kind center has a vision of improving the health and function of people with disabilities through encouraging access, increasing participation, and promoting adherence to recreation, exercise and sports.
UAB Nutrition researchers are investigating whether calorie restriction or intermittent fasting can slow the aging process.
A four-year grant from NIH will fund a clinical trial that will test new approaches to cognitive rehabilitation in adults with stroke.
Given the rising rates of obesity and diabetes, semaglutide could be used effectively to reduce the burden of these chronic diseases.
New funding will advance research on the role of diet and race in knee arthritis pain and pain sensitivity, respectively, in transgender community.
The follow-up study will take a bench-to-bedside approach
The UAB Marnix E. Heersink School of Medicine leadership team outlined key research focus areas to ensure continued growth over the next five to seven years.
This novel finding will help guide successful therapeutic design and strategies for acute kidney injury and chronic kidney disease.
Knockout of TXNIP improves diabetes-associated hyperglycemia and hyperglucagonemia.
Published results suggest the COVID-19 pandemic exacerbated the slow increase in pediatric Type 2 diabetes.
New research seeks to navigate therapeutic resistance for glioblastoma, a type of a severe brain cancer.
The clinically approved drug ruxolitinib suppressed a mouse model of melanoma that is resistant to immune checkpoint blockers.
The UAB projects will investigate was to improve and increase the use of artificial intelligence in biomedical research.
Owsley and McGwin will lead three data collection sites in the collection of data to inform machine learning approaches to provide critical insights into the endemic condition Type 2 diabetes mellitus.
The study, an exception from informed consent trial, will compare whole blood to blood components in the treatment of traumatic injuries.
UAB researchers show there is no longer a connection between the previously linked gene and elevated blood pressure in those of African ancestry.
UAB is participating in a multi-center clinical trial that will dig deeper into the connection between hypertension and salt intake.
Noninvasive ventilation is possible in infants at limits of viability. But unlike in slightly older preterm infants, noninvasive ventilation did not show an advantage in infants of 22 weeks-0 days to 23 weeks-6 days gestational age.
Researchers from UAB and other institutions are seeking to better understand the aging differences between males and females.
Carbohydrates are directly linked to the development of Type 2 diabetes, but a higher-carb diet is underused in research models.
The new technique to predict seizure clusters could, if confirmed, have a profound impact on patients with drug-resistant epilepsy who are prone to seizure clusters.