Are you between the ages of 18-60?

The UAB Office of Psychiatric Research is actively recruiting participants for our studies and wants to connect with you on our research! Whether you are needing someone to talk to, or even have no history of mental health conditions and are just wanting to further knowledge within the medical and mental health field, we would love to get you involved!

Our studies can be broken down into two different categories:

1) TREATMENT STUDIES – Our Treatment Studies are designed to evaluate the effectiveness of new antidepressants on individuals living with Major Depressive Disorder or Treatment-Resistant Depression.

2) NON-TREATMENT STUDIES – Our Non-Treatment Studies do NOT involve testing a new medication or intervention. Instead, these studies focus on understanding behaviors and experiences of mental health conditions via interviews, tests, or surveys.

COMPENSATION IS PROVIDED!

For more information, please reach out to the UAB Office of Psychiatric Research at (205) 934-2484 or go to: https://tinyurl.com/UABpsychiatricresearch and our team will be in contact with you shortly!

Do you experience mild to moderate anxiety?
Want to learn calligraphy?
Help us explore the effects of guided calligraphy training on mental health!

Check eligibility and sign up here: https://sites.uab.edu/calligraphyresearch

BENEFITS
Learn calligraphy with live instructor • Free online calligraphy training course • Free calligraphy supplies • Drawings for gift cards • Improve manual dexterity

PURPOSE
This is a pilot study to assess the feasibility of performing virtually administered art therapy research, as well as a preliminary study to explore whether calligraphy training affects anxiety levels in healthy individuals with mild to moderate anxiety.

TIME & LOCATION
All meetings and training sessions will be held on Zoom. Participation includes up to a total of 15 hours of time over 12 calendar weeks—an intro meeting, 4 training sessions, a debriefing meeting, and 15 minutes a day of practice--5 days a week for 4 weeks. Pending full recruitment, training classes will be held in January-February 2025.

HOW TO ENROLL
To learn more, check eligibility and sign up, click here: https://sites.uab.edu/calligraphyresearch

Join us at the Alabama Vaccine Research Clinic at UAB! We are seeking participants who were assigned male at birth, are 18 years or older, are not living with HIV, have had receptive anal intercourse (RAI) and regularly douche before intercourse. Participants must not have taken oral or injectable PrEP (pre-exposure prophylaxis) for 8 weeks prior to screening. Our clinical trial will help in the development of an on-demand PrEP in the form of a rectal douche. Your involvement will include simple procedures such as medical and sexual history collection, blood and urine sample testing, a physical exam, and receiving PrEP products in the form of an oral pill and a douche. Compensation will be available for your time and effort. If you are interested, please call 205-934-6777, 205-975-2839 or email avrc@uabmc.edu. You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/

Interested in being part of vision rehabilitation research for healthy older adults aged 50-59 to lay the foundation of using a new device?

Here is an overview of what our study will involve!

The purpose of this study?

• Calculate baseline data for Bioness Integrated Therapy System (BITS) and identify its clinical implications in treating visual impairments.
• Compare the baseline data of Bioness Integrated Therapy System (BITS) to Dynavision for visual scanning.

Who are we looking for?

• Healthy adults aged 50-59 without physical, visual, or cognitive impairment and with no history of seizures or balance problems.
• Adults who are able to walk without assistive devices and are English speakers.

What would you have to do in 60 minutes?

• Fill out a short survey for demographic data.
• Quick functional screening of upper extremities.
• Perform four tests on BITS.
• Perform four tests on Dynavision.

Participants will receive a $25 gift card.

To participate in the study, please fill out this short survey:
https://uab.co1.qualtrics.com/jfe/form/SV_exEYGMKXxc230p0

For more information, please contact us at almulhim@uab.edu

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.

We are looking for volunteers to participate in a clinical study to advance lupus treatment.

If you are interested in seeing if you may qualify for an ongoing clinical study, please contact Christina Ndolo at cmndolo@uabmc.edu.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

If you are currently taking antidepressant medications but still struggle with depression, you may qualify for a new clinical research study. The study is evaluating an oral investigational medication for depression that can be taken with your current antidepressant medication. For more information and to see if you're eligible to participate, please call 205-975-8542 or 205-934-2484.

TRANSCEND-T2D-2 is a clinical research study for people with type 2 diabetes. This study will test if an investigational medicine (the medicine being studied) can help with blood glucose (sugar) and weight management compared with an existing treatment for type 2 diabetes. You may be able to join the research study if you are aged 18 years or older, have type 2 diabetes, have been taking 1500mg or more of metformin each day for at least 3 months (with or without SGLT2i), have a BMI of 25 or more, have HbA1c levels of 7.0% to 10.5%. For more information, please contact Tracie Thomas, RN, at 205-996-4015 or email tthoma@uab.edu

Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

About the Clinical Trial:

The purpose of this NIH funded trial is to examine the effects of three different diabetes treatments to determine if they improve night-time blood sugars.

This Trial Involves:

• A screening visit that includes a blood draw, urine test and physical exam
• Treatment with Metformin, Insulin Glargine (long-acting insulin) or the experimental drug Dorzagliatin which is FDA-approved for research, for up to 8 weeks
• 2-4 inpatient visits/ including two overnight stays at the Clinical Research Unit at 15th floor of Jefferson Tower.

All visits to be completed within a three-month period. Study-related tests and procedures are provided free of charge. Participants will be compensated up to $2,500 for study completion. All Participants must be Diagnosed with type 2 DM and Not on any type of insulin therapy.

Please contact Kathryn Hollifield-Laumer at khollifield@uabmc.edu or co-investigators Chanel Mason at 205-934-1921 or cnmason@uabmc.edu, or Alaaeldin Hodhod at ahodhod@uabmc.edu.

We are currently recruiting participants aged 18-30 with normal or corrected to normal vision and participants aged 18-89 with Macular Degeneration/Stargardt's Disease for a clinical research study that aims to understand how individuals learn to use their peripheral vision following the loss of central vision. This study is being conducted in the Civitan International Research Center and involves a total of 27 in-person visits over the course of 1.5 to 3 months. There are 2 MRI visits (1 at the beginning of the study and one at the end), 5 assessment visits (3 baseline assessments and 2 post assessments), and a total of 20 training sessions (in between the baselines and the post assessments). Compensation for full participation in this study is $350.

This is a great opportunity for all to gain experience participating in a clinical research study. All participation would not only contribute to advancing our understanding of perceptual learning and how the brain processes vision, but also holds the potential to improve outcomes for those with central vision loss.

If you or someone you know may be interested, please consider participating.

For more information or to express interest, please email mcmaxwell@uabmc.edu or text or call 205-410-4041, or visit go.uab.edu/brainstudy to sign up!

Thank you for your time and consideration!

Participants between the ages of 35 and 65 are needed for this study. The purpose of the study is to fill in what we don’t know about how schizophrenia affects people as they get older. We want to find out what we can do to help older individuals with schizophrenia live better lives. The study includes 4 visits over the course of two weeks. The screening visit will take 2 hours. The first study visit will take 3 hours. The second study visit will take 2 hours. The third study visit will take 9 hours. This study will include: a clinical interview, cognitive batteries, questionnaires and assessments related to your daily and psychiatric functioning, two 90 minute MRI scans of your brain, a fasting blood draw, and a urine drug screen and pregnancy test (for females). Compensation is up to $310. TO SEE IF YOU QUALIFY PLEASE CONTACT (205) 934-8203.

Join us at the Alabama Vaccine Research Clinic at UAB! We are looking for volunteers to join a Phase 1 clinical trial to test the safety and immune response of a new HIV vaccine. The study is for adults who are HIV-negative, in good health, and aged 18 to 55. Procedures will include blood draws and injections of the study vaccine, as well as the collection of white blood cells through a procedure called leukapheresis. Participants will be compensated for their time in this study. The study vaccine will not give you HIV. If you are interested, please call 205-934-6777 or email avrc@uabmc.edu. You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/.

Our study is looking for physically active and inactive postmenopausal women of Black or White race. We are testing the impact of race, exercise habits, and living conditions on heart disease risk in postmenopausal women. Participation only involves two, one-hour long visits to the UAB Center for Exercise Medicine and offers compensation up to $200. If you are interested in participating, please call McKenna Tharpe at (205) 996-3005.

Participants Needed. We are recruiting individuals who have experienced a stroke and are able to walk with minimal restriction and also age similar control participants that have NOT experienced a stroke between the ages of 18-89 for a research study on walking. The focus of this study is to understand how to optimize the delivery of a combined strength and aerobic training regimen to individuals with post stroke hemiparesis and reduce overuse and inefficiencies associated with the unaffected leg while walking. If you qualify, your participation in the study will span a single study visit, with a total time commitment of 3 hours. You will be compensated for your time. Please e-mail Christopher Hurt at cphurt@uab.edu or contact him by phone at 205-934-8517 if you are interested.

Study Information:

• Are you 18-60 years of age living with HIV, and want to be a part of a vaccine study?
• Is your viral load suppressed/undetectable?
• Are you able to receive a vaccine?
• Are you generally healthy?
• Are you willing to temporarily stop taking antiretrovirals?

You may qualify for a study looking at testing an experimental HIV vaccine with an experimental adjuvant to see how the immune responses change among participants who do an antiretroviral analytical treatment interruption (ATI) compared to those who do not. Compensation at each study visit will be provided for time and travel. Transportation services are also available upon request. If interested, please email sspaulding@uabmc.edu.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.

Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.

If you’ve been feeling stuck and longing for relief, you may be eligible to receive dedicated medical attention, an investigational therapeutic and compensation for your involvement in an innovative research study.

We're conducting clinical research in depression to learn how individuals’ brain biology impacts response to treatment, with the goal to help people find relief faster. You do not need to already have a diagnosis to participate.

If you’re currently taking medication, you are likely still eligible for our studies and don’t have to stop your existing treatment regimen.

For more information about this trial and to see if you qualify, please contact Kristine at kristinepike@uabmc.edu or 205-975-8542.

Major Depressive Disorder is a mental health condition characterized by periods of low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. The purpose of this clinical research study is to evaluate the safety and effectiveness of an investigational drug for Major Depressive Disorder, also known as Major Depression. Study participation may include several clinic visits over a period of up to 5 months with an opportunity to conduct some visits either virtually or in-clinic. Qualified participants will receive compensation for their time.

For more information about this trial and to see if you qualify, please contact Kristine at kristinepike@uabmc.edu or 205-975-8542.

Are you:
• A woman on parole, probation, or recently released from prison or jail?
• A woman who has used drugs?
• Interested in learning about a way to protect yourself against HIV?

You may qualify for a paid research study at the University of Alabama at Birmingham, in partnership with Yale University.
• Participate in confidential study interviews at our research office.
• Earn $50 for each interview, up to $225 for participating in the study.

Fill out our contact survey at: https://yalesurvey.ca1.qualtrics.com/jfe/form/SV_d7sAjr6GDsjiJng?Q_CHL=qr

Or you may call: (205) 934-2851 or Email: AthenaStudy@uabmc.edu