What is i2b2?
i2b2 (Informatics for Integrating Biology and the Bedside) is an NIH-funded National Center for Biomedical Computing based at Partners HealthCare System. i2b2 was developed as a scalable informatics framework designed for translational research. i2b2 was primarily designed for cohort identification, allowing users to perform an enterprise-wide search on a de-identified repository of health information to determine the existence of a set of patients meeting certain inclusion or exclusion criteria.
Access to clinical data through i2b2 involves several easy steps. After setting up their acces, authorized CCTS i2b2 users can access the system to obtain:
- Summary data sets (useful for finding aggregate population characteristics or for estimating the number of patients at UAB who might be eligible as subjects for a planned clinical study)
- Detailed data sets (useful for enrolling subjects in a study or to explore research questions using retrospective data)
Access i2b2
Access to i2b2 is available to authorized CCTS users and UAB personnel via BlazerID, but also requires validation of several other items. Detailed instructions can be found here.
1. Successful completion of at least one of the following courses
- HIPAA Privacy/Security Training
- IRB Investigator 101 Initial Training
- IRB Investigator 101 Continuing Ed
2. Submit an i2b2 Access Request Form
Please note: If you are not a Principal Investigator, you will require supervisor approval.
3. Acknowledgement of Restriction on the Use of Limited Data Sets
- Log-on to the UAB Learning Management System
- Search the catalog for "Acknowledgement of Restrictions on the use of limited data sets" and enroll in this course
(Note: This must be completed once a year.)
4. Your access will be activated within 48 hours of receiving your request if all applicable requirements are complete.
Support Materials:
- i2b2 Manual
- i2b2 Frequently Asked Questions
For those researchers who prefer the flexibility of learning online and/or who wish to refresh their i2b2 knowledge, CCTS offers i2b2 training videos.
If you experience any difficulty please contact Matt Wyatt